PHC2-NLRP4 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-PHC2/NLRP4-08764 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PHC2-NLRP4 Gene Fusion FISH Probecan detect the fusion of PHC2 and NLRP4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PHC2-NLRP4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Polyhomeotic Homolog 2 |
Gene Summary 1 |
In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 1 |
Locus 1 |
1p35.1 |
Coordinates 1 |
This gene maps to 33789223-33841194 in GRCh37 coordinates. |
Gene Name 2 |
NLR Family Pyrin Domain Containing 4 |
Gene Summary 2 |
The protein encoded by this gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). This gene product has a demonstrated role as a negative regulator of autophagy and type I interferon signaling pathways as a result of protein interactions with its NACHT domain. The PYD domain has also been shown to be important in the inhibition of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells). [provided by RefSeq, Dec 2016] |
Chromosome 2 |
Chromosome19 |
Locus 2 |
19q13.43 |
Coordinates 2 |
This gene maps to 56347943-56393220 in GRCh37 coordinates. |
Associated Diseases |
Uterine Corpus Endometrial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PHC2/NLRP4-08764-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PHC2/NLRP4-08764-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PHC2/NLRP4-08764-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PHC2/NLRP4-08764-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PHC2/NLRP4-08764-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PHC2/NLRP4-08764-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PHC2/NLRP4-08764-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PHC2/NLRP4-08764-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PHC2/NLRP4-08764-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PHC2/NLRP4-08764-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PHC2/NLRP4-08764-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PHC2/NLRP4-08764-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PHC2/NLRP4-08764-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PHC2/NLRP4-08764-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PHC2/NLRP4-08764-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PHC2/NLRP4-08764-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PHC2/NLRP4-08764-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PHC2/NLRP4-08764-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PHC2/NLRP4-08764-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PHC2/NLRP4-08764-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PHC2/NLRP4-08764-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PHC2/NLRP4-08764-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PHC2/NLRP4-08764-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PHC2/NLRP4-08764-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PHC2/NLRP4-08764-AQAQ |
467nm;467nm |
418nm;418nm |
|
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