PGAP3-GRB7 Gene Fusion FISH Probe
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Catalog: |
GFFP-PGAP3/GRB7-08784 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PGAP3-GRB7 Gene Fusion FISH Probecan detect the fusion of PGAP3 and GRB7 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PGAP3-GRB7 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Growth Factor Receptor Bound Protein 7 |
Gene Summary 1 |
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q12 |
Coordinates 1 |
This gene maps to 37894161-37903538 in GRCh37 coordinates. |
Gene Name 2 |
Post-GPI Attachment To Proteins 3 |
Gene Summary 2 |
This gene encodes a glycosylphosphatidylinositol (GPI)-specific phospholipase that primarily localizes to the Golgi apparatus. This ubiquitously expressed gene is predicted to encode a seven-transmembrane protein that removes unsaturated fatty acids from the sn-2 position of GPI. The remodeling of the constituent fatty acids on GPI is thought to be important for the proper association between GPI-anchored proteins and lipid rafts. The tethering of proteins to plasma membranes via posttranslational GPI-anchoring is thought to play a role in protein sorting and trafficking. Mutations in this gene cause an autosomal recessive form of neurologic hyperphosphatasia with cognitive disability (HPMRS4). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17q12 |
Coordinates 2 |
This gene maps to 37827374-37844310 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PGAP3/GRB7-08784-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PGAP3/GRB7-08784-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PGAP3/GRB7-08784-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PGAP3/GRB7-08784-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PGAP3/GRB7-08784-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PGAP3/GRB7-08784-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PGAP3/GRB7-08784-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PGAP3/GRB7-08784-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PGAP3/GRB7-08784-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PGAP3/GRB7-08784-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PGAP3/GRB7-08784-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PGAP3/GRB7-08784-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PGAP3/GRB7-08784-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PGAP3/GRB7-08784-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PGAP3/GRB7-08784-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PGAP3/GRB7-08784-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PGAP3/GRB7-08784-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PGAP3/GRB7-08784-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PGAP3/GRB7-08784-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PGAP3/GRB7-08784-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PGAP3/GRB7-08784-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PGAP3/GRB7-08784-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PGAP3/GRB7-08784-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PGAP3/GRB7-08784-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PGAP3/GRB7-08784-AQAQ |
467nm;467nm |
418nm;418nm |
|
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