PFKFB3-PALM2-AKAP2 Gene Fusion FISH Probe
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| Catalog: |
GFFP-PFKFB3/PALM2/AKAP2-08790 |
| Classification: |
Gene Fusion FISH Probes |
| Description: |
The PFKFB3-PALM2-AKAP2 Gene Fusion FISH Probecan detect the fusion of PFKFB3 and PALM2-AKAP2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Category: |
Gene Fusion FISH Probes |
| Application: |
PFKFB3-PALM2-AKAP2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name 1 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| Gene Summary 1 |
The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016] |
| Chromosome 1 |
Chromosome 10 |
| Locus 1 |
10p15.1 |
| Coordinates 1 |
This gene maps to 6186842-6277507 in GRCh37 coordinates. |
| Gene Name 2 |
PALM2-AKAP2 Readthrough |
| Gene Summary 2 |
PALM2-AKAP2 mRNAs are naturally occurring read-through products of the neighboring PALM2 and AKAP2 genes that belong to the paralemmin downstream gene (PDG) family. The significance of these read-through mRNAs and the function the resulting fusion protein products have not yet been determined. Naturally occurring mutations in this gene are associated with human height. [provided by RefSeq, May 2017] |
| Chromosome 2 |
Chromosome9 |
| Locus 2 |
9q31.3 |
| Coordinates 2 |
This gene maps to 112542576-112934791 in GRCh37 coordinates. |
| Associated Diseases |
Sarcoma |
| Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
RE; RE
|
GFFP-PFKFB3/PALM2/AKAP2-08790-RERE |
599nm;599nm |
580nm;580nm |
|
| 2 |
RE; OR
|
GFFP-PFKFB3/PALM2/AKAP2-08790-REOR |
599nm;573nm |
580nm;548nm |
|
| 3 |
RE; GO
|
GFFP-PFKFB3/PALM2/AKAP2-08790-REGO |
599nm;551nm |
580nm;525nm |
|
| 4 |
RE; GR
|
GFFP-PFKFB3/PALM2/AKAP2-08790-REGR |
599nm;515nm |
580nm;491nm |
|
| 5 |
RE; AQ
|
GFFP-PFKFB3/PALM2/AKAP2-08790-REAQ |
599nm;467nm |
580nm;418nm |
|
| 6 |
OR; RE
|
GFFP-PFKFB3/PALM2/AKAP2-08790-ORRE |
573nm;599nm |
548nm;580nm |
|
| 7 |
OR; OR
|
GFFP-PFKFB3/PALM2/AKAP2-08790-OROR |
573nm;573nm |
548nm;548nm |
|
| 8 |
OR; GO
|
GFFP-PFKFB3/PALM2/AKAP2-08790-ORGO |
573nm;551nm |
548nm;525nm |
|
| 9 |
OR; GR
|
GFFP-PFKFB3/PALM2/AKAP2-08790-ORGR |
573nm;515nm |
548nm;491nm |
|
| 10 |
OR; AQ
|
GFFP-PFKFB3/PALM2/AKAP2-08790-ORAQ |
573nm;467nm |
548nm;418nm |
|
| 11 |
GO; RE
|
GFFP-PFKFB3/PALM2/AKAP2-08790-GORE |
551nm;599nm |
525nm;580nm |
|
| 12 |
GO; OR
|
GFFP-PFKFB3/PALM2/AKAP2-08790-GOOR |
551nm;573nm |
525nm;548nm |
|
| 13 |
GO; GO
|
GFFP-PFKFB3/PALM2/AKAP2-08790-GOGO |
551nm;551nm |
525nm;525nm |
|
| 14 |
GO; GR
|
GFFP-PFKFB3/PALM2/AKAP2-08790-GOGR |
551nm;515nm |
525nm;491nm |
|
| 15 |
GO; AQ
|
GFFP-PFKFB3/PALM2/AKAP2-08790-GOAQ |
551nm;467nm |
525nm;418nm |
|
| 16 |
GR; RE
|
GFFP-PFKFB3/PALM2/AKAP2-08790-GRRE |
515nm;599nm |
491nm;580nm |
|
| 17 |
GR; OR
|
GFFP-PFKFB3/PALM2/AKAP2-08790-GROR |
515nm;573nm |
491nm;548nm |
|
| 18 |
GR; GO
|
GFFP-PFKFB3/PALM2/AKAP2-08790-GRGO |
515nm;551nm |
491nm;525nm |
|
| 19 |
GR; GR
|
GFFP-PFKFB3/PALM2/AKAP2-08790-GRGR |
515nm;515nm |
491nm;491nm |
|
| 20 |
GR; AQ
|
GFFP-PFKFB3/PALM2/AKAP2-08790-GRAQ |
515nm;467nm |
491nm;418nm |
|
| 21 |
AQ; RE
|
GFFP-PFKFB3/PALM2/AKAP2-08790-AQRE |
467nm;599nm |
418nm;580nm |
|
| 22 |
AQ; OR
|
GFFP-PFKFB3/PALM2/AKAP2-08790-AQOR |
467nm;573nm |
418nm;548nm |
|
| 23 |
AQ; GO
|
GFFP-PFKFB3/PALM2/AKAP2-08790-AQGO |
467nm;551nm |
418nm;525nm |
|
| 24 |
AQ; GR
|
GFFP-PFKFB3/PALM2/AKAP2-08790-AQGR |
467nm;515nm |
418nm;491nm |
|
| 25 |
AQ; AQ
|
GFFP-PFKFB3/PALM2/AKAP2-08790-AQAQ |
467nm;467nm |
418nm;418nm |
|
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