PFKFB1-ALAS2 Gene Fusion FISH Probe
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Catalog: |
GFFP-PFKFB1/ALAS2-08794 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PFKFB1-ALAS2 Gene Fusion FISH Probecan detect the fusion of PFKFB1 and ALAS2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PFKFB1-ALAS2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
5'-aminolevulinate Synthase 2 |
Gene Summary 1 |
The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome X |
Locus 1 |
Xp11.21 |
Coordinates 1 |
This gene maps to 55035487-55057497 in GRCh37 coordinates. |
Gene Name 2 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
Gene Summary 2 |
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012] |
Chromosome 2 |
ChromosomeX |
Locus 2 |
Xp11.21 |
Coordinates 2 |
This gene maps to 54959589-55020511 in GRCh37 coordinates. |
Associated Diseases |
Liver Hepatocellular Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PFKFB1/ALAS2-08794-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PFKFB1/ALAS2-08794-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PFKFB1/ALAS2-08794-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PFKFB1/ALAS2-08794-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PFKFB1/ALAS2-08794-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PFKFB1/ALAS2-08794-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PFKFB1/ALAS2-08794-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PFKFB1/ALAS2-08794-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PFKFB1/ALAS2-08794-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PFKFB1/ALAS2-08794-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PFKFB1/ALAS2-08794-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PFKFB1/ALAS2-08794-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PFKFB1/ALAS2-08794-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PFKFB1/ALAS2-08794-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PFKFB1/ALAS2-08794-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PFKFB1/ALAS2-08794-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PFKFB1/ALAS2-08794-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PFKFB1/ALAS2-08794-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PFKFB1/ALAS2-08794-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PFKFB1/ALAS2-08794-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PFKFB1/ALAS2-08794-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PFKFB1/ALAS2-08794-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PFKFB1/ALAS2-08794-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PFKFB1/ALAS2-08794-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PFKFB1/ALAS2-08794-AQAQ |
467nm;467nm |
418nm;418nm |
|
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