PENK-PLAT Gene Fusion FISH Probe
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Catalog: |
GFFP-PENK/PLAT-14430 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PENK-PLAT Gene Fusion FISH Probecan detect the fusion of PENK and PLAT genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PENK-PLAT Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Proenkephalin |
Gene Summary 1 |
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the pentapeptide opioids Met-enkephalin and Leu-enkephalin, which are stored in synaptic vesicles, then released into the synapse where they bind to mu- and delta-opioid receptors to modulate the perception of pain. Other non-opioid cleavage products may function in distinct biological activities. [provided by RefSeq, Jul 2015] |
Chromosome 1 |
Chromosome 8 |
Locus 1 |
8q12.1 |
Coordinates 1 |
This gene maps to 57353512-57359282 in GRCh37 coordinates. |
Gene Name 2 |
Plasminogen Activator, Tissue Type |
Gene Summary 2 |
This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
Chromosome 2 |
Chromosome8 |
Locus 2 |
8p11.21 |
Coordinates 2 |
This gene maps to 42032235-42065194 in GRCh37 coordinates. |
Associated Diseases |
Pheochromocytoma And Paraganglioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PENK/PLAT-14430-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PENK/PLAT-14430-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PENK/PLAT-14430-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PENK/PLAT-14430-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PENK/PLAT-14430-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PENK/PLAT-14430-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PENK/PLAT-14430-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PENK/PLAT-14430-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PENK/PLAT-14430-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PENK/PLAT-14430-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PENK/PLAT-14430-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PENK/PLAT-14430-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PENK/PLAT-14430-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PENK/PLAT-14430-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PENK/PLAT-14430-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PENK/PLAT-14430-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PENK/PLAT-14430-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PENK/PLAT-14430-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PENK/PLAT-14430-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PENK/PLAT-14430-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PENK/PLAT-14430-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PENK/PLAT-14430-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PENK/PLAT-14430-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PENK/PLAT-14430-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PENK/PLAT-14430-AQAQ |
467nm;467nm |
418nm;418nm |
|
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