PEMT-TOP3A Gene Fusion FISH Probe
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Catalog: |
GFFP-PEMT/TOP3A-08818 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PEMT-TOP3A Gene Fusion FISH Probecan detect the fusion of PEMT and TOP3A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PEMT-TOP3A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
DNA Topoisomerase III Alpha |
Gene Summary 1 |
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17p11.2 |
Coordinates 1 |
This gene maps to 18177234-18218321 in GRCh37 coordinates. |
Gene Name 2 |
Phosphatidylethanolamine N-methyltransferase |
Gene Summary 2 |
Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17p11.2 |
Coordinates 2 |
This gene maps to 17408876-17494994 in GRCh37 coordinates. |
Associated Diseases |
Prostate Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PEMT/TOP3A-08818-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PEMT/TOP3A-08818-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PEMT/TOP3A-08818-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PEMT/TOP3A-08818-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PEMT/TOP3A-08818-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PEMT/TOP3A-08818-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PEMT/TOP3A-08818-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PEMT/TOP3A-08818-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PEMT/TOP3A-08818-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PEMT/TOP3A-08818-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PEMT/TOP3A-08818-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PEMT/TOP3A-08818-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PEMT/TOP3A-08818-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PEMT/TOP3A-08818-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PEMT/TOP3A-08818-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PEMT/TOP3A-08818-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PEMT/TOP3A-08818-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PEMT/TOP3A-08818-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PEMT/TOP3A-08818-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PEMT/TOP3A-08818-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PEMT/TOP3A-08818-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PEMT/TOP3A-08818-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PEMT/TOP3A-08818-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PEMT/TOP3A-08818-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PEMT/TOP3A-08818-AQAQ |
467nm;467nm |
418nm;418nm |
|
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