PDZRN3-THRB Gene Fusion FISH Probe
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Catalog: |
GFFP-PDZRN3/THRB-08828 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PDZRN3-THRB Gene Fusion FISH Probecan detect the fusion of PDZRN3 and THRB genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PDZRN3-THRB Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Thyroid Hormone Receptor Beta |
Gene Summary 1 |
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 3 |
Locus 1 |
3p24.2 |
Coordinates 1 |
This gene maps to 24158644-24536313 in GRCh37 coordinates. |
Gene Name 2 |
PDZ Domain Containing Ring Finger 3 |
Gene Summary 2 |
This gene encodes a member of the LNX (Ligand of Numb Protein-X) family of RING-type ubiquitin E3 ligases. This protein may function in vascular morphogenesis and the differentiation of adipocytes, osteoblasts and myoblasts. This protein may be targeted for degradation by the human papilloma virus E6 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
Chromosome 2 |
Chromosome3 |
Locus 2 |
3p13 |
Coordinates 2 |
This gene maps to 73431651-73674072 in GRCh37 coordinates. |
Associated Diseases |
Prostate Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PDZRN3/THRB-08828-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PDZRN3/THRB-08828-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PDZRN3/THRB-08828-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PDZRN3/THRB-08828-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PDZRN3/THRB-08828-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PDZRN3/THRB-08828-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PDZRN3/THRB-08828-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PDZRN3/THRB-08828-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PDZRN3/THRB-08828-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PDZRN3/THRB-08828-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PDZRN3/THRB-08828-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PDZRN3/THRB-08828-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PDZRN3/THRB-08828-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PDZRN3/THRB-08828-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PDZRN3/THRB-08828-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PDZRN3/THRB-08828-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PDZRN3/THRB-08828-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PDZRN3/THRB-08828-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PDZRN3/THRB-08828-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PDZRN3/THRB-08828-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PDZRN3/THRB-08828-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PDZRN3/THRB-08828-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PDZRN3/THRB-08828-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PDZRN3/THRB-08828-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PDZRN3/THRB-08828-AQAQ |
467nm;467nm |
418nm;418nm |
|
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