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PDE4D-EFNA5 Gene Fusion FISH Probe

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Catalog: GFFP-PDE4D/EFNA5-08590
Classification: Gene Fusion FISH Probes
Description: The PDE4D-EFNA5 Gene Fusion FISH Probecan detect the fusion of PDE4D and EFNA5 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PDE4D-EFNA5 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Ephrin A5
Gene Summary 1 Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 5
Locus 1 5q21.3
Coordinates 1 This gene maps to 106712589-107006596 in GRCh37 coordinates.
Gene Name 2 Phosphodiesterase 4D
Gene Summary 2 This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]
Chromosome 2 Chromosome5
Locus 2 5q11.2-q12.1
Coordinates 2 This gene maps to 58264865-59783925 in GRCh37 coordinates.
Associated Diseases Skin Cutaneous Melanoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PDE4D/EFNA5-08590-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PDE4D/EFNA5-08590-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PDE4D/EFNA5-08590-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PDE4D/EFNA5-08590-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PDE4D/EFNA5-08590-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PDE4D/EFNA5-08590-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PDE4D/EFNA5-08590-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PDE4D/EFNA5-08590-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PDE4D/EFNA5-08590-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PDE4D/EFNA5-08590-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PDE4D/EFNA5-08590-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PDE4D/EFNA5-08590-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PDE4D/EFNA5-08590-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PDE4D/EFNA5-08590-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PDE4D/EFNA5-08590-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PDE4D/EFNA5-08590-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PDE4D/EFNA5-08590-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PDE4D/EFNA5-08590-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PDE4D/EFNA5-08590-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PDE4D/EFNA5-08590-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PDE4D/EFNA5-08590-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PDE4D/EFNA5-08590-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PDE4D/EFNA5-08590-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PDE4D/EFNA5-08590-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PDE4D/EFNA5-08590-AQAQ 467nm;467nm 418nm;418nm

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