PDE4B-JAK1 Gene Fusion FISH Probe
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Catalog: |
GFFP-PDE4B/JAK1-08591 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PDE4B-JAK1 Gene Fusion FISH Probecan detect the fusion of PDE4B and JAK1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PDE4B-JAK1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Janus Kinase 1 |
Gene Summary 1 |
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
Chromosome 1 |
Chromosome 1 |
Locus 1 |
1p31.3 |
Coordinates 1 |
This gene maps to 65298905-65432187 in GRCh37 coordinates. |
Gene Name 2 |
Phosphodiesterase 4B |
Gene Summary 2 |
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1p31.3 |
Coordinates 2 |
This gene maps to 66258192-66840262 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PDE4B/JAK1-08591-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PDE4B/JAK1-08591-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PDE4B/JAK1-08591-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PDE4B/JAK1-08591-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PDE4B/JAK1-08591-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PDE4B/JAK1-08591-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PDE4B/JAK1-08591-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PDE4B/JAK1-08591-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PDE4B/JAK1-08591-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PDE4B/JAK1-08591-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PDE4B/JAK1-08591-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PDE4B/JAK1-08591-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PDE4B/JAK1-08591-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PDE4B/JAK1-08591-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PDE4B/JAK1-08591-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PDE4B/JAK1-08591-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PDE4B/JAK1-08591-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PDE4B/JAK1-08591-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PDE4B/JAK1-08591-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PDE4B/JAK1-08591-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PDE4B/JAK1-08591-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PDE4B/JAK1-08591-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PDE4B/JAK1-08591-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PDE4B/JAK1-08591-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PDE4B/JAK1-08591-AQAQ |
467nm;467nm |
418nm;418nm |
|
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