PDE3A-CCT2 Gene Fusion FISH Probe
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Catalog: |
GFFP-PDE3A/CCT2-08599 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PDE3A-CCT2 Gene Fusion FISH Probecan detect the fusion of PDE3A and CCT2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PDE3A-CCT2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Phosphodiesterase 3A |
Gene Summary 1 |
This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12p12.2 |
Coordinates 1 |
This gene maps to 20522196-20833881 in GRCh37 coordinates. |
Gene Name 2 |
Chaperonin Containing TCP1 Subunit 2 |
Gene Summary 2 |
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
Chromosome 2 |
Chromosome12 |
Locus 2 |
12q15 |
Coordinates 2 |
This gene maps to 69979207-69995357 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PDE3A/CCT2-08599-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PDE3A/CCT2-08599-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PDE3A/CCT2-08599-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PDE3A/CCT2-08599-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PDE3A/CCT2-08599-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PDE3A/CCT2-08599-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PDE3A/CCT2-08599-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PDE3A/CCT2-08599-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PDE3A/CCT2-08599-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PDE3A/CCT2-08599-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PDE3A/CCT2-08599-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PDE3A/CCT2-08599-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PDE3A/CCT2-08599-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PDE3A/CCT2-08599-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PDE3A/CCT2-08599-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PDE3A/CCT2-08599-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PDE3A/CCT2-08599-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PDE3A/CCT2-08599-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PDE3A/CCT2-08599-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PDE3A/CCT2-08599-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PDE3A/CCT2-08599-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PDE3A/CCT2-08599-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PDE3A/CCT2-08599-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PDE3A/CCT2-08599-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PDE3A/CCT2-08599-AQAQ |
467nm;467nm |
418nm;418nm |
|
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