PDE10A-DDX23 Gene Fusion FISH Probe
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Catalog: |
GFFP-PDE10A/DDX23-08602 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PDE10A-DDX23 Gene Fusion FISH Probecan detect the fusion of PDE10A and DDX23 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PDE10A-DDX23 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
DEAD-box Helicase 23 |
Gene Summary 1 |
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12q13.12 |
Coordinates 1 |
This gene maps to 49223538-49245957 in GRCh37 coordinates. |
Gene Name 2 |
Phosphodiesterase 10A |
Gene Summary 2 |
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011] |
Chromosome 2 |
Chromosome6 |
Locus 2 |
6q27 |
Coordinates 2 |
This gene maps to 165740777-166075584 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PDE10A/DDX23-08602-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PDE10A/DDX23-08602-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PDE10A/DDX23-08602-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PDE10A/DDX23-08602-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PDE10A/DDX23-08602-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PDE10A/DDX23-08602-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PDE10A/DDX23-08602-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PDE10A/DDX23-08602-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PDE10A/DDX23-08602-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PDE10A/DDX23-08602-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PDE10A/DDX23-08602-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PDE10A/DDX23-08602-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PDE10A/DDX23-08602-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PDE10A/DDX23-08602-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PDE10A/DDX23-08602-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PDE10A/DDX23-08602-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PDE10A/DDX23-08602-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PDE10A/DDX23-08602-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PDE10A/DDX23-08602-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PDE10A/DDX23-08602-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PDE10A/DDX23-08602-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PDE10A/DDX23-08602-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PDE10A/DDX23-08602-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PDE10A/DDX23-08602-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PDE10A/DDX23-08602-AQAQ |
467nm;467nm |
418nm;418nm |
|
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