PDCD6-TERT Gene Fusion FISH Probe
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Catalog: |
GFFP-PDCD6/TERT-15408 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PDCD6-TERT Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PDCD6-TERT Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Telomerase Reverse Transcriptase |
Gene Summary 1 |
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 5 |
Locus 1 |
5p15.33 |
Coordinates 1 |
This gene maps to 1253286-1295162in GRCh37 coordinates. |
Gene Name 2 |
Programmed Cell Death 6 |
Gene Summary 2 |
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012] |
Chromosome 2 |
Chromosome5 |
Locus 2 |
5p15.33 |
Coordinates 2 |
This gene maps to 271735-315089 in GRCh37 coordinates. |
Associated Diseases |
Kidney Renal Clear Cell Carcinoma; Kidney Chromophobe |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PDCD6/TERT-15408-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PDCD6/TERT-15408-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PDCD6/TERT-15408-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PDCD6/TERT-15408-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PDCD6/TERT-15408-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PDCD6/TERT-15408-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PDCD6/TERT-15408-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PDCD6/TERT-15408-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PDCD6/TERT-15408-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PDCD6/TERT-15408-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PDCD6/TERT-15408-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PDCD6/TERT-15408-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PDCD6/TERT-15408-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PDCD6/TERT-15408-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PDCD6/TERT-15408-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PDCD6/TERT-15408-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PDCD6/TERT-15408-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PDCD6/TERT-15408-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PDCD6/TERT-15408-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PDCD6/TERT-15408-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PDCD6/TERT-15408-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PDCD6/TERT-15408-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PDCD6/TERT-15408-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PDCD6/TERT-15408-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PDCD6/TERT-15408-AQAQ |
467nm;467nm |
418nm;418nm |
|
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