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PDCD2L-CACNA1A Gene Fusion FISH Probe

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Catalog: GFFP-PDCD2L/CACNA1A-08612
Classification: Gene Fusion FISH Probes
Description: The PDCD2L-CACNA1A Gene Fusion FISH Probecan detect the fusion of PDCD2L and CACNA1A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PDCD2L-CACNA1A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Calcium Voltage-gated Channel Subunit Alpha1 A
Gene Summary 1 Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits polymorphic variation due to (CAG)n-repeats. Multiple transcript variants encoding different isoforms have been found for this gene. In one set of transcript variants, the (CAG)n-repeats occur in the 3' UTR, and are not associated with any disease. But in another set of variants, an insertion extends the coding region to include the (CAG)n-repeats which encode a polyglutamine tract. Expansion of the (CAG)n-repeats from the normal 4-18 to 21-33 in the coding region is associated with spinocerebellar ataxia 6. [provided by RefSeq, Jul 2016]
Chromosome 1 Chromosome 19
Locus 1 19p13.13
Coordinates 1 This gene maps to 13317255-13617274 in GRCh37 coordinates.
Gene Name 2 Programmed Cell Death 2 Like
Gene Summary 2 The Programmed Cell Death 2 Like (PDCD2L) gene is located on chr19 :34895302-34917072 at 19q13.11.
Chromosome 2 Chromosome19
Locus 2 19q13.11
Coordinates 2 This gene maps to 34895302-34917072 in GRCh37 coordinates.
Associated Diseases Stomach Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PDCD2L/CACNA1A-08612-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PDCD2L/CACNA1A-08612-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PDCD2L/CACNA1A-08612-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PDCD2L/CACNA1A-08612-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PDCD2L/CACNA1A-08612-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PDCD2L/CACNA1A-08612-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PDCD2L/CACNA1A-08612-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PDCD2L/CACNA1A-08612-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PDCD2L/CACNA1A-08612-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PDCD2L/CACNA1A-08612-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PDCD2L/CACNA1A-08612-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PDCD2L/CACNA1A-08612-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PDCD2L/CACNA1A-08612-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PDCD2L/CACNA1A-08612-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PDCD2L/CACNA1A-08612-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PDCD2L/CACNA1A-08612-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PDCD2L/CACNA1A-08612-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PDCD2L/CACNA1A-08612-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PDCD2L/CACNA1A-08612-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PDCD2L/CACNA1A-08612-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PDCD2L/CACNA1A-08612-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PDCD2L/CACNA1A-08612-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PDCD2L/CACNA1A-08612-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PDCD2L/CACNA1A-08612-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PDCD2L/CACNA1A-08612-AQAQ 467nm;467nm 418nm;418nm

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