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PCDHGA6-JMJD1C Gene Fusion FISH Probe

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Catalog: GFFP-PCDHGA6/JMJD1C-08653
Classification: Gene Fusion FISH Probes
Description: The PCDHGA6-JMJD1C Gene Fusion FISH Probecan detect the fusion of PCDHGA6 and JMJD1C genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PCDHGA6-JMJD1C Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Protocadherin Gamma Subfamily A, 6
Gene Summary 1 This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 5
Locus 1 5q31.3
Coordinates 1 This gene maps to 140753650-140892546 in GRCh37 coordinates.
Gene Name 2 Jumonji Domain Containing 1C
Gene Summary 2 The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Chromosome 2 Chromosome10
Locus 2 10q21.3
Coordinates 2 This gene maps to 64926987-65225722 in GRCh37 coordinates.
Associated Diseases Skin Cutaneous Melanoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PCDHGA6/JMJD1C-08653-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PCDHGA6/JMJD1C-08653-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PCDHGA6/JMJD1C-08653-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PCDHGA6/JMJD1C-08653-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PCDHGA6/JMJD1C-08653-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PCDHGA6/JMJD1C-08653-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PCDHGA6/JMJD1C-08653-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PCDHGA6/JMJD1C-08653-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PCDHGA6/JMJD1C-08653-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PCDHGA6/JMJD1C-08653-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PCDHGA6/JMJD1C-08653-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PCDHGA6/JMJD1C-08653-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PCDHGA6/JMJD1C-08653-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PCDHGA6/JMJD1C-08653-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PCDHGA6/JMJD1C-08653-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PCDHGA6/JMJD1C-08653-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PCDHGA6/JMJD1C-08653-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PCDHGA6/JMJD1C-08653-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PCDHGA6/JMJD1C-08653-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PCDHGA6/JMJD1C-08653-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PCDHGA6/JMJD1C-08653-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PCDHGA6/JMJD1C-08653-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PCDHGA6/JMJD1C-08653-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PCDHGA6/JMJD1C-08653-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PCDHGA6/JMJD1C-08653-AQAQ 467nm;467nm 418nm;418nm

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