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PCDHA11-ANKHD1 Gene Fusion FISH Probe

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Catalog: GFFP-PCDHA11/ANKHD1-08654
Classification: Gene Fusion FISH Probes
Description: The PCDHA11-ANKHD1 Gene Fusion FISH Probecan detect the fusion of PCDHA11 and ANKHD1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: PCDHA11-ANKHD1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Ankyrin Repeat And KH Domain Containing 1
Gene Summary 1 This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Sep 2010]
Chromosome 1 Chromosome 5
Locus 1 5q31.3
Coordinates 1 This gene maps to 139781398-139919441 in GRCh37 coordinates.
Gene Name 2 Protocadherin Alpha 11
Gene Summary 2 This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome5
Locus 2 5q31.3
Coordinates 2 This gene maps to 140247830-140391929 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-PCDHA11/ANKHD1-08654-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-PCDHA11/ANKHD1-08654-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-PCDHA11/ANKHD1-08654-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-PCDHA11/ANKHD1-08654-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-PCDHA11/ANKHD1-08654-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-PCDHA11/ANKHD1-08654-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-PCDHA11/ANKHD1-08654-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-PCDHA11/ANKHD1-08654-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-PCDHA11/ANKHD1-08654-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-PCDHA11/ANKHD1-08654-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-PCDHA11/ANKHD1-08654-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-PCDHA11/ANKHD1-08654-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-PCDHA11/ANKHD1-08654-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-PCDHA11/ANKHD1-08654-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-PCDHA11/ANKHD1-08654-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-PCDHA11/ANKHD1-08654-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-PCDHA11/ANKHD1-08654-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-PCDHA11/ANKHD1-08654-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-PCDHA11/ANKHD1-08654-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-PCDHA11/ANKHD1-08654-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-PCDHA11/ANKHD1-08654-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-PCDHA11/ANKHD1-08654-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-PCDHA11/ANKHD1-08654-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-PCDHA11/ANKHD1-08654-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-PCDHA11/ANKHD1-08654-AQAQ 467nm;467nm 418nm;418nm

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