PAX8-NFE2L2 Gene Fusion FISH Probe
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Catalog: |
GFFP-PAX8/NFE2L2-08346 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PAX8-NFE2L2 Gene Fusion FISH Probecan detect the fusion of PAX8 and NFE2L2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PAX8-NFE2L2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Nuclear Factor, Erythroid 2 Like 2 |
Gene Summary 1 |
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015] |
Chromosome 1 |
Chromosome 2 |
Locus 1 |
2q31.2 |
Coordinates 1 |
This gene maps to 178095032-178129859 in GRCh37 coordinates. |
Gene Name 2 |
Paired Box 8 |
Gene Summary 2 |
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010] |
Chromosome 2 |
Chromosome2 |
Locus 2 |
2q13 |
Coordinates 2 |
This gene maps to 113973573-114036498 in GRCh37 coordinates. |
Associated Diseases |
Thyroid Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PAX8/NFE2L2-08346-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PAX8/NFE2L2-08346-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PAX8/NFE2L2-08346-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PAX8/NFE2L2-08346-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PAX8/NFE2L2-08346-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PAX8/NFE2L2-08346-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PAX8/NFE2L2-08346-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PAX8/NFE2L2-08346-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PAX8/NFE2L2-08346-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PAX8/NFE2L2-08346-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PAX8/NFE2L2-08346-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PAX8/NFE2L2-08346-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PAX8/NFE2L2-08346-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PAX8/NFE2L2-08346-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PAX8/NFE2L2-08346-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PAX8/NFE2L2-08346-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PAX8/NFE2L2-08346-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PAX8/NFE2L2-08346-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PAX8/NFE2L2-08346-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PAX8/NFE2L2-08346-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PAX8/NFE2L2-08346-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PAX8/NFE2L2-08346-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PAX8/NFE2L2-08346-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PAX8/NFE2L2-08346-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PAX8/NFE2L2-08346-AQAQ |
467nm;467nm |
418nm;418nm |
|
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