PAK1-PDGFD Gene Fusion FISH Probe
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Catalog: |
GFFP-PAK1/PDGFD-08441 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PAK1-PDGFD Gene Fusion FISH Probecan detect the fusion of PAK1 and PDGFD genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PAK1-PDGFD Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
P21 (RAC1) Activated Kinase 1 |
Gene Summary 1 |
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11q13.5-q14.1 |
Coordinates 1 |
This gene maps to 77033059-77185108 in GRCh37 coordinates. |
Gene Name 2 |
Platelet Derived Growth Factor D |
Gene Summary 2 |
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q22.3 |
Coordinates 2 |
This gene maps to 103777913-104035027 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PAK1/PDGFD-08441-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PAK1/PDGFD-08441-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PAK1/PDGFD-08441-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PAK1/PDGFD-08441-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PAK1/PDGFD-08441-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PAK1/PDGFD-08441-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PAK1/PDGFD-08441-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PAK1/PDGFD-08441-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PAK1/PDGFD-08441-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PAK1/PDGFD-08441-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PAK1/PDGFD-08441-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PAK1/PDGFD-08441-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PAK1/PDGFD-08441-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PAK1/PDGFD-08441-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PAK1/PDGFD-08441-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PAK1/PDGFD-08441-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PAK1/PDGFD-08441-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PAK1/PDGFD-08441-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PAK1/PDGFD-08441-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PAK1/PDGFD-08441-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PAK1/PDGFD-08441-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PAK1/PDGFD-08441-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PAK1/PDGFD-08441-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PAK1/PDGFD-08441-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PAK1/PDGFD-08441-AQAQ |
467nm;467nm |
418nm;418nm |
|
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