PAH-METAP2 Gene Fusion FISH Probe
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Catalog: |
GFFP-PAH/METAP2-08456 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The PAH-METAP2 Gene Fusion FISH Probecan detect the fusion of PAH and METAP2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
PAH-METAP2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Phenylalanine Hydroxylase |
Gene Summary 1 |
This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. [provided by RefSeq, Aug 2017] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12q23.2 |
Coordinates 1 |
This gene maps to 103232103-103311381 in GRCh37 coordinates. |
Gene Name 2 |
Methionyl Aminopeptidase 2 |
Gene Summary 2 |
The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
Chromosome 2 |
Chromosome12 |
Locus 2 |
12q22 |
Coordinates 2 |
This gene maps to 95867821-95909613 in GRCh37 coordinates. |
Associated Diseases |
Adrenocortical Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-PAH/METAP2-08456-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-PAH/METAP2-08456-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-PAH/METAP2-08456-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-PAH/METAP2-08456-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-PAH/METAP2-08456-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-PAH/METAP2-08456-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-PAH/METAP2-08456-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-PAH/METAP2-08456-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-PAH/METAP2-08456-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-PAH/METAP2-08456-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-PAH/METAP2-08456-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-PAH/METAP2-08456-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-PAH/METAP2-08456-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-PAH/METAP2-08456-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-PAH/METAP2-08456-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-PAH/METAP2-08456-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-PAH/METAP2-08456-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-PAH/METAP2-08456-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-PAH/METAP2-08456-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-PAH/METAP2-08456-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-PAH/METAP2-08456-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-PAH/METAP2-08456-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-PAH/METAP2-08456-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-PAH/METAP2-08456-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-PAH/METAP2-08456-AQAQ |
467nm;467nm |
418nm;418nm |
|
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