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P4HA1-NODAL Gene Fusion FISH Probe

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Catalog: GFFP-P4HA1/NODAL-08497
Classification: Gene Fusion FISH Probes
Description: The P4HA1-NODAL Gene Fusion FISH Probecan detect the fusion of P4HA1 and NODAL genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: P4HA1-NODAL Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Nodal Growth Differentiation Factor
Gene Summary 1 This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. [provided by RefSeq, Aug 2016]
Chromosome 1 Chromosome 10
Locus 1 10q22.1
Coordinates 1 This gene maps to 72191691-72201465 in GRCh37 coordinates.
Gene Name 2 Prolyl 4-hydroxylase Subunit Alpha 1
Gene Summary 2 This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome10
Locus 2 10q22.1
Coordinates 2 This gene maps to 74766979-74856732 in GRCh37 coordinates.
Associated Diseases Prostate Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-P4HA1/NODAL-08497-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-P4HA1/NODAL-08497-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-P4HA1/NODAL-08497-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-P4HA1/NODAL-08497-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-P4HA1/NODAL-08497-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-P4HA1/NODAL-08497-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-P4HA1/NODAL-08497-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-P4HA1/NODAL-08497-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-P4HA1/NODAL-08497-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-P4HA1/NODAL-08497-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-P4HA1/NODAL-08497-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-P4HA1/NODAL-08497-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-P4HA1/NODAL-08497-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-P4HA1/NODAL-08497-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-P4HA1/NODAL-08497-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-P4HA1/NODAL-08497-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-P4HA1/NODAL-08497-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-P4HA1/NODAL-08497-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-P4HA1/NODAL-08497-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-P4HA1/NODAL-08497-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-P4HA1/NODAL-08497-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-P4HA1/NODAL-08497-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-P4HA1/NODAL-08497-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-P4HA1/NODAL-08497-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-P4HA1/NODAL-08497-AQAQ 467nm;467nm 418nm;418nm

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