OAZ2-RBPMS2 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-OAZ2/RBPMS2-08279 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The OAZ2-RBPMS2 Gene Fusion FISH Probecan detect the fusion of OAZ2 and RBPMS2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
OAZ2-RBPMS2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Ornithine Decarboxylase Antizyme 2 |
Gene Summary 1 |
The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamines. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 2, the second member of the antizyme family. Like antizyme 1, antizyme 2 has broad tissue distribution, inhibits ODC activity and polyamine uptake, and stimulates ODC degradation in vivo; however, it fails to promote ODC degradation in vitro. Antizyme 2 is expressed at lower levels than antizyme 1, but is evolutionary more conserved, suggesting it likely has an important biological role. Studies also show different subcellular localization of antizymes 1 and 2, indicating specific function for each antizyme in discrete compartments of the cell. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2014] |
Chromosome 1 |
Chromosome 15 |
Locus 1 |
15q22.31 |
Coordinates 1 |
This gene maps to 64979772-64995462 in GRCh37 coordinates. |
Gene Name 2 |
RNA Binding Protein With Multiple Splicing 2 |
Gene Summary 2 |
The protein encoded by this gene is a member of the RNA recognition motif (RRM)-containing protein family and is involved in the development and dedifferentiation of digestive smooth muscle cells. The encoded protein functions as a homodimer and indirectly inhibits the bone morphogenetic protein pathway. [provided by RefSeq, Aug 2016] |
Chromosome 2 |
Chromosome15 |
Locus 2 |
15q22.31 |
Coordinates 2 |
This gene maps to 65032094-65067770 in GRCh37 coordinates. |
Associated Diseases |
Brain Lower Grade Glioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-OAZ2/RBPMS2-08279-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-OAZ2/RBPMS2-08279-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-OAZ2/RBPMS2-08279-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-OAZ2/RBPMS2-08279-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-OAZ2/RBPMS2-08279-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-OAZ2/RBPMS2-08279-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-OAZ2/RBPMS2-08279-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-OAZ2/RBPMS2-08279-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-OAZ2/RBPMS2-08279-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-OAZ2/RBPMS2-08279-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-OAZ2/RBPMS2-08279-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-OAZ2/RBPMS2-08279-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-OAZ2/RBPMS2-08279-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-OAZ2/RBPMS2-08279-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-OAZ2/RBPMS2-08279-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-OAZ2/RBPMS2-08279-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-OAZ2/RBPMS2-08279-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-OAZ2/RBPMS2-08279-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-OAZ2/RBPMS2-08279-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-OAZ2/RBPMS2-08279-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-OAZ2/RBPMS2-08279-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-OAZ2/RBPMS2-08279-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-OAZ2/RBPMS2-08279-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-OAZ2/RBPMS2-08279-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-OAZ2/RBPMS2-08279-AQAQ |
467nm;467nm |
418nm;418nm |
|
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