OAZ1-YBX2 Gene Fusion FISH Probe
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Catalog: |
GFFP-OAZ1/YBX2-08281 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The OAZ1-YBX2 Gene Fusion FISH Probecan detect the fusion of OAZ1 and YBX2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
OAZ1-YBX2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Ornithine Decarboxylase Antizyme 1 |
Gene Summary 1 |
The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs; and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene. [provided by RefSeq, Dec 2014] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19p13.3 |
Coordinates 1 |
This gene maps to 2269519-2273487 in GRCh37 coordinates. |
Gene Name 2 |
Y-box Binding Protein 2 |
Gene Summary 2 |
This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15. [provided by RefSeq, Feb 2012] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17p13.1 |
Coordinates 2 |
This gene maps to 7191570-7197876 in GRCh37 coordinates. |
Associated Diseases |
Liver Hepatocellular Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-OAZ1/YBX2-08281-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-OAZ1/YBX2-08281-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-OAZ1/YBX2-08281-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-OAZ1/YBX2-08281-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-OAZ1/YBX2-08281-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-OAZ1/YBX2-08281-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-OAZ1/YBX2-08281-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-OAZ1/YBX2-08281-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-OAZ1/YBX2-08281-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-OAZ1/YBX2-08281-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-OAZ1/YBX2-08281-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-OAZ1/YBX2-08281-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-OAZ1/YBX2-08281-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-OAZ1/YBX2-08281-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-OAZ1/YBX2-08281-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-OAZ1/YBX2-08281-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-OAZ1/YBX2-08281-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-OAZ1/YBX2-08281-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-OAZ1/YBX2-08281-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-OAZ1/YBX2-08281-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-OAZ1/YBX2-08281-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-OAZ1/YBX2-08281-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-OAZ1/YBX2-08281-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-OAZ1/YBX2-08281-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-OAZ1/YBX2-08281-AQAQ |
467nm;467nm |
418nm;418nm |
|
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