NXN-WRAP53 Gene Fusion FISH Probe
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Catalog: |
GFFP-NXN/WRAP53-14397 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The NXN-WRAP53 Gene Fusion FISH Probecan detect the fusion of NXN and WRAP53 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
NXN-WRAP53 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
WD Repeat Containing Antisense To TP53 |
Gene Summary 1 |
This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17p13.1 |
Coordinates 1 |
This gene maps to 7589388-7606820 in GRCh37 coordinates. |
Gene Name 2 |
Nucleoredoxin |
Gene Summary 2 |
This gene encodes a member of the thioredoxin superfamily, a group of small, multifunctional redox-active proteins. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. The encoded protein acts a redox-dependent regulator of the Wnt signaling pathway and is involved in cell growth and differentiation. [provided by RefSeq, Sep 2015] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17p13.3 |
Coordinates 2 |
This gene maps to 702552-882998 in GRCh37 coordinates. |
Associated Diseases |
Head And Neck Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-NXN/WRAP53-14397-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-NXN/WRAP53-14397-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-NXN/WRAP53-14397-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-NXN/WRAP53-14397-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-NXN/WRAP53-14397-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-NXN/WRAP53-14397-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-NXN/WRAP53-14397-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-NXN/WRAP53-14397-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-NXN/WRAP53-14397-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-NXN/WRAP53-14397-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-NXN/WRAP53-14397-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-NXN/WRAP53-14397-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-NXN/WRAP53-14397-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-NXN/WRAP53-14397-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-NXN/WRAP53-14397-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-NXN/WRAP53-14397-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-NXN/WRAP53-14397-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-NXN/WRAP53-14397-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-NXN/WRAP53-14397-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-NXN/WRAP53-14397-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-NXN/WRAP53-14397-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-NXN/WRAP53-14397-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-NXN/WRAP53-14397-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-NXN/WRAP53-14397-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-NXN/WRAP53-14397-AQAQ |
467nm;467nm |
418nm;418nm |
|
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