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NXF1-STX5 Gene Fusion FISH Probe

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Catalog: GFFP-NXF1/STX5-15390
Classification: Gene Fusion FISH Probes
Description: The NXF1-STX5 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NXF1-STX5 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Syntaxin 5
Gene Summary 1 This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Chromosome 1 Chromosome 11
Locus 1 11q12.3
Coordinates 1 This gene maps to 62574368-62599560in GRCh37 coordinates.
Gene Name 2 Nuclear RNA Export Factor 1
Gene Summary 2 This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome11
Locus 2 11q12.3
Coordinates 2 This gene maps to 62559597-62572964 in GRCh37 coordinates.
Associated Diseases Liver Hepatocellular Carcinoma; Uterine Carcinosarcoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NXF1/STX5-15390-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NXF1/STX5-15390-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NXF1/STX5-15390-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NXF1/STX5-15390-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NXF1/STX5-15390-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NXF1/STX5-15390-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NXF1/STX5-15390-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NXF1/STX5-15390-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NXF1/STX5-15390-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NXF1/STX5-15390-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NXF1/STX5-15390-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NXF1/STX5-15390-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NXF1/STX5-15390-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NXF1/STX5-15390-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NXF1/STX5-15390-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NXF1/STX5-15390-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NXF1/STX5-15390-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NXF1/STX5-15390-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NXF1/STX5-15390-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NXF1/STX5-15390-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NXF1/STX5-15390-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NXF1/STX5-15390-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NXF1/STX5-15390-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NXF1/STX5-15390-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NXF1/STX5-15390-AQAQ 467nm;467nm 418nm;418nm

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