NTRK3-ETV6 Gene Fusion FISH Probe
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Catalog: |
GFFP-NTRK3/ETV6-08057 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The NTRK3-ETV6 Gene Fusion FISH Probecan detect the fusion of NTRK3 and ETV6 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
NTRK3-ETV6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
ETS Variant 6 |
Gene Summary 1 |
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12p13.2 |
Coordinates 1 |
This gene maps to 11802787-12048325 in GRCh37 coordinates. |
Gene Name 2 |
Neurotrophic Receptor Tyrosine Kinase 3 |
Gene Summary 2 |
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] |
Chromosome 2 |
Chromosome15 |
Locus 2 |
15q25.3 |
Coordinates 2 |
This gene maps to 88419987-88799962 in GRCh37 coordinates. |
Associated Diseases |
Thyroid Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-NTRK3/ETV6-08057-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-NTRK3/ETV6-08057-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-NTRK3/ETV6-08057-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-NTRK3/ETV6-08057-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-NTRK3/ETV6-08057-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-NTRK3/ETV6-08057-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-NTRK3/ETV6-08057-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-NTRK3/ETV6-08057-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-NTRK3/ETV6-08057-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-NTRK3/ETV6-08057-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-NTRK3/ETV6-08057-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-NTRK3/ETV6-08057-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-NTRK3/ETV6-08057-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-NTRK3/ETV6-08057-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-NTRK3/ETV6-08057-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-NTRK3/ETV6-08057-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-NTRK3/ETV6-08057-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-NTRK3/ETV6-08057-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-NTRK3/ETV6-08057-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-NTRK3/ETV6-08057-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-NTRK3/ETV6-08057-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-NTRK3/ETV6-08057-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-NTRK3/ETV6-08057-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-NTRK3/ETV6-08057-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-NTRK3/ETV6-08057-AQAQ |
467nm;467nm |
418nm;418nm |
|
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