NSMCE2-DCLRE1C Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-NSMCE2/DCLRE1C-08086 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The NSMCE2-DCLRE1C Gene Fusion FISH Probecan detect the fusion of NSMCE2 and DCLRE1C genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
NSMCE2-DCLRE1C Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
DNA Cross-link Repair 1C |
Gene Summary 1 |
This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
Chromosome 1 |
Chromosome 10 |
Locus 1 |
10p13 |
Coordinates 1 |
This gene maps to 14948870-14996094 in GRCh37 coordinates. |
Gene Name 2 |
NSE2/MMS21 Homolog, SMC5-SMC6 Complex SUMO Ligase |
Gene Summary 2 |
This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance. [provided by RefSeq, Mar 2017] |
Chromosome 2 |
Chromosome8 |
Locus 2 |
8q24.13 |
Coordinates 2 |
This gene maps to 126104082-126379367 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-NSMCE2/DCLRE1C-08086-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-NSMCE2/DCLRE1C-08086-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-NSMCE2/DCLRE1C-08086-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-NSMCE2/DCLRE1C-08086-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-NSMCE2/DCLRE1C-08086-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-NSMCE2/DCLRE1C-08086-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-NSMCE2/DCLRE1C-08086-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-NSMCE2/DCLRE1C-08086-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-NSMCE2/DCLRE1C-08086-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-NSMCE2/DCLRE1C-08086-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-NSMCE2/DCLRE1C-08086-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-NSMCE2/DCLRE1C-08086-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-NSMCE2/DCLRE1C-08086-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-NSMCE2/DCLRE1C-08086-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-NSMCE2/DCLRE1C-08086-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-NSMCE2/DCLRE1C-08086-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-NSMCE2/DCLRE1C-08086-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-NSMCE2/DCLRE1C-08086-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-NSMCE2/DCLRE1C-08086-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-NSMCE2/DCLRE1C-08086-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-NSMCE2/DCLRE1C-08086-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-NSMCE2/DCLRE1C-08086-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-NSMCE2/DCLRE1C-08086-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-NSMCE2/DCLRE1C-08086-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-NSMCE2/DCLRE1C-08086-AQAQ |
467nm;467nm |
418nm;418nm |
|
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