NSMCE2-COL22A1 Gene Fusion FISH Probe
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Catalog: |
GFFP-NSMCE2/COL22A1-08087 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The NSMCE2-COL22A1 Gene Fusion FISH Probecan detect the fusion of NSMCE2 and COL22A1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
NSMCE2-COL22A1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Collagen Type XXII Alpha 1 Chain |
Gene Summary 1 |
This gene encodes member of the collagen family which is thought to contribute to the stabilization of myotendinous junctions and strengthen skeletal muscle attachments during contractile activity. It belongs to the fibril-associated collagens with interrupted triple helix (FACIT) subset of the collagen superfamily, which associate with collagen fibers through their C-terminal collagenous domains and mediate protein-protein interactions through their N-terminal noncollagenous domains. The encoded protein is deposited in the basement membrane zone of the myotendinous junction which is present only at the tissue junctions of muscles, tendons, the heart, articular cartilage, and skin. A knockdown of the orthologous zebrafish gene induces a muscular dystrophy by disruption of the myotendinous junction. [provided by RefSeq, May 2017] |
Chromosome 1 |
Chromosome 8 |
Locus 1 |
8q24.23-q24.3 |
Coordinates 1 |
This gene maps to 139600477-139926236 in GRCh37 coordinates. |
Gene Name 2 |
NSE2/MMS21 Homolog, SMC5-SMC6 Complex SUMO Ligase |
Gene Summary 2 |
This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance. [provided by RefSeq, Mar 2017] |
Chromosome 2 |
Chromosome8 |
Locus 2 |
8q24.13 |
Coordinates 2 |
This gene maps to 126104082-126379367 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-NSMCE2/COL22A1-08087-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-NSMCE2/COL22A1-08087-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-NSMCE2/COL22A1-08087-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-NSMCE2/COL22A1-08087-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-NSMCE2/COL22A1-08087-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-NSMCE2/COL22A1-08087-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-NSMCE2/COL22A1-08087-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-NSMCE2/COL22A1-08087-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-NSMCE2/COL22A1-08087-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-NSMCE2/COL22A1-08087-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-NSMCE2/COL22A1-08087-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-NSMCE2/COL22A1-08087-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-NSMCE2/COL22A1-08087-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-NSMCE2/COL22A1-08087-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-NSMCE2/COL22A1-08087-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-NSMCE2/COL22A1-08087-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-NSMCE2/COL22A1-08087-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-NSMCE2/COL22A1-08087-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-NSMCE2/COL22A1-08087-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-NSMCE2/COL22A1-08087-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-NSMCE2/COL22A1-08087-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-NSMCE2/COL22A1-08087-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-NSMCE2/COL22A1-08087-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-NSMCE2/COL22A1-08087-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-NSMCE2/COL22A1-08087-AQAQ |
467nm;467nm |
418nm;418nm |
|
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