NOTCH2-PSMA5 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-NOTCH2/PSMA5-08164 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The NOTCH2-PSMA5 Gene Fusion FISH Probecan detect the fusion of NOTCH2 and PSMA5 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
NOTCH2-PSMA5 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Notch 2 |
Gene Summary 1 |
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] |
Chromosome 1 |
Chromosome 1 |
Locus 1 |
1p12 |
Coordinates 1 |
This gene maps to 120454175-120612317 in GRCh37 coordinates. |
Gene Name 2 |
Proteasome Subunit Alpha 5 |
Gene Summary 2 |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1p13.3 |
Coordinates 2 |
This gene maps to 109941652-109969108 in GRCh37 coordinates. |
Associated Diseases |
Ovarian Serous Cystadenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-NOTCH2/PSMA5-08164-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-NOTCH2/PSMA5-08164-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-NOTCH2/PSMA5-08164-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-NOTCH2/PSMA5-08164-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-NOTCH2/PSMA5-08164-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-NOTCH2/PSMA5-08164-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-NOTCH2/PSMA5-08164-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-NOTCH2/PSMA5-08164-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-NOTCH2/PSMA5-08164-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-NOTCH2/PSMA5-08164-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-NOTCH2/PSMA5-08164-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-NOTCH2/PSMA5-08164-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-NOTCH2/PSMA5-08164-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-NOTCH2/PSMA5-08164-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-NOTCH2/PSMA5-08164-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-NOTCH2/PSMA5-08164-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-NOTCH2/PSMA5-08164-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-NOTCH2/PSMA5-08164-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-NOTCH2/PSMA5-08164-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-NOTCH2/PSMA5-08164-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-NOTCH2/PSMA5-08164-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-NOTCH2/PSMA5-08164-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-NOTCH2/PSMA5-08164-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-NOTCH2/PSMA5-08164-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-NOTCH2/PSMA5-08164-AQAQ |
467nm;467nm |
418nm;418nm |
|
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