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NKX2-1-SLC25A21 Gene Fusion FISH Probe

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Catalog: GFFP-NKX2/1/SLC25A21-07829
Classification: Gene Fusion FISH Probes
Description: The NKX2-1-SLC25A21 Gene Fusion FISH Probecan detect the fusion of NKX2-1 and SLC25A21 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NKX2-1-SLC25A21 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 NK2 Homeobox 1
Gene Summary 1 This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]
Chromosome 1 Chromosome 14
Locus 1 14q13.3
Coordinates 1 This gene maps to 36985603-36989430 in GRCh37 coordinates.
Gene Name 2 Solute Carrier Family 25 Member 21
Gene Summary 2 SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004]
Chromosome 2 Chromosome14
Locus 2 14q13.3
Coordinates 2 This gene maps to 37147125-37641865 in GRCh37 coordinates.
Associated Diseases Lung Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NKX2/1/SLC25A21-07829-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NKX2/1/SLC25A21-07829-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NKX2/1/SLC25A21-07829-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NKX2/1/SLC25A21-07829-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NKX2/1/SLC25A21-07829-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NKX2/1/SLC25A21-07829-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NKX2/1/SLC25A21-07829-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NKX2/1/SLC25A21-07829-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NKX2/1/SLC25A21-07829-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NKX2/1/SLC25A21-07829-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NKX2/1/SLC25A21-07829-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NKX2/1/SLC25A21-07829-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NKX2/1/SLC25A21-07829-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NKX2/1/SLC25A21-07829-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NKX2/1/SLC25A21-07829-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NKX2/1/SLC25A21-07829-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NKX2/1/SLC25A21-07829-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NKX2/1/SLC25A21-07829-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NKX2/1/SLC25A21-07829-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NKX2/1/SLC25A21-07829-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NKX2/1/SLC25A21-07829-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NKX2/1/SLC25A21-07829-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NKX2/1/SLC25A21-07829-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NKX2/1/SLC25A21-07829-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NKX2/1/SLC25A21-07829-AQAQ 467nm;467nm 418nm;418nm

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