NKX2-1-SLC25A21 Gene Fusion FISH Probe

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Catalog:	GFFP-NKX2/1/SLC25A21-07829
Classification:	Gene Fusion FISH Probes
Description:	The NKX2-1-SLC25A21 Gene Fusion FISH Probecan detect the fusion of NKX2-1 and SLC25A21 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Application:	NKX2-1-SLC25A21 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	7-10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name 1	NK2 Homeobox 1
Gene Summary 1	This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]
Chromosome 1	Chromosome 14
Locus 1	14q13.3
Coordinates 1	This gene maps to 36985603-36989430 in GRCh37 coordinates.
Gene Name 2	Solute Carrier Family 25 Member 21
Gene Summary 2	SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004]
Chromosome 2	Chromosome14
Locus 2	14q13.3
Coordinates 2	This gene maps to 37147125-37641865 in GRCh37 coordinates.
Associated Diseases	Lung Squamous Cell Carcinoma
Species	Human

Dye Colors:

RE RE RE OR RE GO RE GR RE AQ OR RE OR OR OR GO OR GR OR AQ GO RE GO OR GO GO GO GR GO AQ GR RE GR OR GR GO GR GR GR AQ AQ RE AQ OR AQ GO AQ GR AQ AQ

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	RE; RE	GFFP-NKX2/1/SLC25A21-07829-RERE	599nm;599nm	580nm;580nm
2	RE; OR	GFFP-NKX2/1/SLC25A21-07829-REOR	599nm;573nm	580nm;548nm
3	RE; GO	GFFP-NKX2/1/SLC25A21-07829-REGO	599nm;551nm	580nm;525nm
4	RE; GR	GFFP-NKX2/1/SLC25A21-07829-REGR	599nm;515nm	580nm;491nm
5	RE; AQ	GFFP-NKX2/1/SLC25A21-07829-REAQ	599nm;467nm	580nm;418nm
6	OR; RE	GFFP-NKX2/1/SLC25A21-07829-ORRE	573nm;599nm	548nm;580nm
7	OR; OR	GFFP-NKX2/1/SLC25A21-07829-OROR	573nm;573nm	548nm;548nm
8	OR; GO	GFFP-NKX2/1/SLC25A21-07829-ORGO	573nm;551nm	548nm;525nm
9	OR; GR	GFFP-NKX2/1/SLC25A21-07829-ORGR	573nm;515nm	548nm;491nm
10	OR; AQ	GFFP-NKX2/1/SLC25A21-07829-ORAQ	573nm;467nm	548nm;418nm
11	GO; RE	GFFP-NKX2/1/SLC25A21-07829-GORE	551nm;599nm	525nm;580nm
12	GO; OR	GFFP-NKX2/1/SLC25A21-07829-GOOR	551nm;573nm	525nm;548nm
13	GO; GO	GFFP-NKX2/1/SLC25A21-07829-GOGO	551nm;551nm	525nm;525nm
14	GO; GR	GFFP-NKX2/1/SLC25A21-07829-GOGR	551nm;515nm	525nm;491nm
15	GO; AQ	GFFP-NKX2/1/SLC25A21-07829-GOAQ	551nm;467nm	525nm;418nm
16	GR; RE	GFFP-NKX2/1/SLC25A21-07829-GRRE	515nm;599nm	491nm;580nm
17	GR; OR	GFFP-NKX2/1/SLC25A21-07829-GROR	515nm;573nm	491nm;548nm
18	GR; GO	GFFP-NKX2/1/SLC25A21-07829-GRGO	515nm;551nm	491nm;525nm
19	GR; GR	GFFP-NKX2/1/SLC25A21-07829-GRGR	515nm;515nm	491nm;491nm
20	GR; AQ	GFFP-NKX2/1/SLC25A21-07829-GRAQ	515nm;467nm	491nm;418nm
21	AQ; RE	GFFP-NKX2/1/SLC25A21-07829-AQRE	467nm;599nm	418nm;580nm
22	AQ; OR	GFFP-NKX2/1/SLC25A21-07829-AQOR	467nm;573nm	418nm;548nm
23	AQ; GO	GFFP-NKX2/1/SLC25A21-07829-AQGO	467nm;551nm	418nm;525nm
24	AQ; GR	GFFP-NKX2/1/SLC25A21-07829-AQGR	467nm;515nm	418nm;491nm
25	AQ; AQ	GFFP-NKX2/1/SLC25A21-07829-AQAQ	467nm;467nm	418nm;418nm

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