NFKB2-GBF1 Gene Fusion FISH Probe
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Catalog: |
GFFP-NFKB2/GBF1-07941 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The NFKB2-GBF1 Gene Fusion FISH Probecan detect the fusion of NFKB2 and GBF1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
NFKB2-GBF1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Nuclear Factor Kappa B Subunit 2 |
Gene Summary 1 |
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
Chromosome 1 |
Chromosome 10 |
Locus 1 |
10q24.32 |
Coordinates 1 |
This gene maps to 104154228-104162281 in GRCh37 coordinates. |
Gene Name 2 |
Golgi Brefeldin A Resistant Guanine Nucleotide Exchange Factor 1 |
Gene Summary 2 |
This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010] |
Chromosome 2 |
Chromosome10 |
Locus 2 |
10q24.32 |
Coordinates 2 |
This gene maps to 104005254-104142656 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-NFKB2/GBF1-07941-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-NFKB2/GBF1-07941-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-NFKB2/GBF1-07941-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-NFKB2/GBF1-07941-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-NFKB2/GBF1-07941-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-NFKB2/GBF1-07941-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-NFKB2/GBF1-07941-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-NFKB2/GBF1-07941-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-NFKB2/GBF1-07941-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-NFKB2/GBF1-07941-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-NFKB2/GBF1-07941-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-NFKB2/GBF1-07941-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-NFKB2/GBF1-07941-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-NFKB2/GBF1-07941-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-NFKB2/GBF1-07941-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-NFKB2/GBF1-07941-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-NFKB2/GBF1-07941-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-NFKB2/GBF1-07941-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-NFKB2/GBF1-07941-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-NFKB2/GBF1-07941-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-NFKB2/GBF1-07941-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-NFKB2/GBF1-07941-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-NFKB2/GBF1-07941-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-NFKB2/GBF1-07941-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-NFKB2/GBF1-07941-AQAQ |
467nm;467nm |
418nm;418nm |
|
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