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NFKB1-MANBA Gene Fusion FISH Probe

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Catalog: GFFP-NFKB1/MANBA-07942
Classification: Gene Fusion FISH Probes
Description: The NFKB1-MANBA Gene Fusion FISH Probecan detect the fusion of NFKB1 and MANBA genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NFKB1-MANBA Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Mannosidase Beta
Gene Summary 1 This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 4
Locus 1 4q24
Coordinates 1 This gene maps to 103552642-103682151 in GRCh37 coordinates.
Gene Name 2 Nuclear Factor Kappa B Subunit 1
Gene Summary 2 This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed. [provided by RefSeq, Feb 2016]
Chromosome 2 Chromosome4
Locus 2 4q24
Coordinates 2 This gene maps to 103422485-103538459 in GRCh37 coordinates.
Associated Diseases Brain Lower Grade Glioma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NFKB1/MANBA-07942-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NFKB1/MANBA-07942-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NFKB1/MANBA-07942-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NFKB1/MANBA-07942-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NFKB1/MANBA-07942-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NFKB1/MANBA-07942-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NFKB1/MANBA-07942-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NFKB1/MANBA-07942-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NFKB1/MANBA-07942-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NFKB1/MANBA-07942-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NFKB1/MANBA-07942-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NFKB1/MANBA-07942-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NFKB1/MANBA-07942-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NFKB1/MANBA-07942-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NFKB1/MANBA-07942-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NFKB1/MANBA-07942-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NFKB1/MANBA-07942-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NFKB1/MANBA-07942-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NFKB1/MANBA-07942-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NFKB1/MANBA-07942-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NFKB1/MANBA-07942-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NFKB1/MANBA-07942-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NFKB1/MANBA-07942-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NFKB1/MANBA-07942-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NFKB1/MANBA-07942-AQAQ 467nm;467nm 418nm;418nm

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