NF1-PDS5B Gene Fusion FISH Probe
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Catalog: |
GFFP-NF1/PDS5B-07994 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The NF1-PDS5B Gene Fusion FISH Probecan detect the fusion of NF1 and PDS5B genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
NF1-PDS5B Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Neurofibromin 1 |
Gene Summary 1 |
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q11.2 |
Coordinates 1 |
This gene maps to 29421944-29704695 in GRCh37 coordinates. |
Gene Name 2 |
PDS5 Cohesin Associated Factor B |
Gene Summary 2 |
This gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. [provided by RefSeq, Jul 2015] |
Chromosome 2 |
Chromosome13 |
Locus 2 |
13q13.1 |
Coordinates 2 |
This gene maps to 33160563-33352158 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-NF1/PDS5B-07994-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-NF1/PDS5B-07994-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-NF1/PDS5B-07994-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-NF1/PDS5B-07994-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-NF1/PDS5B-07994-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-NF1/PDS5B-07994-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-NF1/PDS5B-07994-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-NF1/PDS5B-07994-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-NF1/PDS5B-07994-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-NF1/PDS5B-07994-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-NF1/PDS5B-07994-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-NF1/PDS5B-07994-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-NF1/PDS5B-07994-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-NF1/PDS5B-07994-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-NF1/PDS5B-07994-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-NF1/PDS5B-07994-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-NF1/PDS5B-07994-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-NF1/PDS5B-07994-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-NF1/PDS5B-07994-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-NF1/PDS5B-07994-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-NF1/PDS5B-07994-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-NF1/PDS5B-07994-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-NF1/PDS5B-07994-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-NF1/PDS5B-07994-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-NF1/PDS5B-07994-AQAQ |
467nm;467nm |
418nm;418nm |
|
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