NEIL3-AGA Gene Fusion FISH Probe
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Catalog: |
GFFP-NEIL3/AGA-07706 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The NEIL3-AGA Gene Fusion FISH Probecan detect the fusion of NEIL3 and AGA genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
NEIL3-AGA Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Aspartylglucosaminidase |
Gene Summary 1 |
This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. This enzyme is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. Mutations in this gene are associated with the lysosomal storage disease aspartylglycosaminuria that results in progressive neurodegeneration. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is subject to proteolytic processing. [provided by RefSeq, Nov 2015] |
Chromosome 1 |
Chromosome 4 |
Locus 1 |
4q34.3 |
Coordinates 1 |
This gene maps to 178351928-178363657 in GRCh37 coordinates. |
Gene Name 2 |
Nei Like DNA Glycosylase 3 |
Gene Summary 2 |
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008] |
Chromosome 2 |
Chromosome4 |
Locus 2 |
4q34.3 |
Coordinates 2 |
This gene maps to 178230990-178284092 in GRCh37 coordinates. |
Associated Diseases |
Bladder Urothelial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-NEIL3/AGA-07706-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-NEIL3/AGA-07706-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-NEIL3/AGA-07706-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-NEIL3/AGA-07706-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-NEIL3/AGA-07706-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-NEIL3/AGA-07706-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-NEIL3/AGA-07706-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-NEIL3/AGA-07706-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-NEIL3/AGA-07706-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-NEIL3/AGA-07706-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-NEIL3/AGA-07706-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-NEIL3/AGA-07706-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-NEIL3/AGA-07706-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-NEIL3/AGA-07706-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-NEIL3/AGA-07706-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-NEIL3/AGA-07706-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-NEIL3/AGA-07706-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-NEIL3/AGA-07706-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-NEIL3/AGA-07706-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-NEIL3/AGA-07706-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-NEIL3/AGA-07706-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-NEIL3/AGA-07706-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-NEIL3/AGA-07706-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-NEIL3/AGA-07706-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-NEIL3/AGA-07706-AQAQ |
467nm;467nm |
418nm;418nm |
|
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