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NEBL-FBXO11 Gene Fusion FISH Probe

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Catalog: GFFP-NEBL/FBXO11-07675
Classification: Gene Fusion FISH Probes
Description: The NEBL-FBXO11 Gene Fusion FISH Probecan detect the fusion of NEBL and FBXO11 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NEBL-FBXO11 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Nebulette
Gene Summary 1 This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Chromosome 1 Chromosome 10
Locus 1 10p12.31
Coordinates 1 This gene maps to 21068902-21463116 in GRCh37 coordinates.
Gene Name 2 F-box Protein 11
Gene Summary 2 This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It can function as an arginine methyltransferase that symmetrically dimethylates arginine residues, and it acts as an adaptor protein to mediate the neddylation of p53, which leads to the suppression of p53 function. This gene is known to be down-regulated in melanocytes from patients with vitiligo, a skin disorder that results in depigmentation. Polymorphisms in this gene are associated with chronic otitis media with effusion and recurrent otitis media (COME/ROM), a hearing loss disorder, and the knockout of the homologous mouse gene results in the deaf mouse mutant Jeff (Jf), a single gene model of otitis media. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]
Chromosome 2 Chromosome2
Locus 2 2p16.3
Coordinates 2 This gene maps to 48034058-48132932 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NEBL/FBXO11-07675-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NEBL/FBXO11-07675-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NEBL/FBXO11-07675-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NEBL/FBXO11-07675-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NEBL/FBXO11-07675-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NEBL/FBXO11-07675-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NEBL/FBXO11-07675-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NEBL/FBXO11-07675-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NEBL/FBXO11-07675-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NEBL/FBXO11-07675-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NEBL/FBXO11-07675-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NEBL/FBXO11-07675-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NEBL/FBXO11-07675-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NEBL/FBXO11-07675-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NEBL/FBXO11-07675-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NEBL/FBXO11-07675-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NEBL/FBXO11-07675-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NEBL/FBXO11-07675-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NEBL/FBXO11-07675-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NEBL/FBXO11-07675-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NEBL/FBXO11-07675-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NEBL/FBXO11-07675-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NEBL/FBXO11-07675-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NEBL/FBXO11-07675-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NEBL/FBXO11-07675-AQAQ 467nm;467nm 418nm;418nm

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