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NCSTN-ATP1A4 Gene Fusion FISH Probe

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Catalog: GFFP-NCSTN/ATP1A4-07768
Classification: Gene Fusion FISH Probes
Description: The NCSTN-ATP1A4 Gene Fusion FISH Probecan detect the fusion of NCSTN and ATP1A4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NCSTN-ATP1A4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 ATPase Na+/K+ Transporting Subunit Alpha 4
Gene Summary 1 The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 1
Locus 1 1q23.2
Coordinates 1 This gene maps to 160121351-160156767 in GRCh37 coordinates.
Gene Name 2 Nicastrin
Gene Summary 2 This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Mutations in this gene are associated with familial acne inversa. A pseudogene of this gene is present on chromosome 21. Alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Feb 2014]
Chromosome 2 Chromosome1
Locus 2 1q23.2
Coordinates 2 This gene maps to 160313062-160328742 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NCSTN/ATP1A4-07768-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NCSTN/ATP1A4-07768-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NCSTN/ATP1A4-07768-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NCSTN/ATP1A4-07768-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NCSTN/ATP1A4-07768-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NCSTN/ATP1A4-07768-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NCSTN/ATP1A4-07768-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NCSTN/ATP1A4-07768-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NCSTN/ATP1A4-07768-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NCSTN/ATP1A4-07768-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NCSTN/ATP1A4-07768-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NCSTN/ATP1A4-07768-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NCSTN/ATP1A4-07768-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NCSTN/ATP1A4-07768-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NCSTN/ATP1A4-07768-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NCSTN/ATP1A4-07768-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NCSTN/ATP1A4-07768-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NCSTN/ATP1A4-07768-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NCSTN/ATP1A4-07768-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NCSTN/ATP1A4-07768-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NCSTN/ATP1A4-07768-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NCSTN/ATP1A4-07768-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NCSTN/ATP1A4-07768-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NCSTN/ATP1A4-07768-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NCSTN/ATP1A4-07768-AQAQ 467nm;467nm 418nm;418nm

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