NCOA3-SULF2 Gene Fusion FISH Probe
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Catalog: |
GFFP-NCOA3/SULF2-07793 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The NCOA3-SULF2 Gene Fusion FISH Probecan detect the fusion of NCOA3 and SULF2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
NCOA3-SULF2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Nuclear Receptor Coactivator 3 |
Gene Summary 1 |
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010] |
Chromosome 1 |
Chromosome 20 |
Locus 1 |
20q13.12 |
Coordinates 1 |
This gene maps to 46130600-46285621 in GRCh37 coordinates. |
Gene Name 2 |
Sulfatase 2 |
Gene Summary 2 |
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008] |
Chromosome 2 |
Chromosome20 |
Locus 2 |
20q13.12 |
Coordinates 2 |
This gene maps to 46286149-46415360 in GRCh37 coordinates. |
Associated Diseases |
Uterine Carcinosarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-NCOA3/SULF2-07793-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-NCOA3/SULF2-07793-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-NCOA3/SULF2-07793-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-NCOA3/SULF2-07793-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-NCOA3/SULF2-07793-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-NCOA3/SULF2-07793-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-NCOA3/SULF2-07793-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-NCOA3/SULF2-07793-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-NCOA3/SULF2-07793-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-NCOA3/SULF2-07793-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-NCOA3/SULF2-07793-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-NCOA3/SULF2-07793-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-NCOA3/SULF2-07793-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-NCOA3/SULF2-07793-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-NCOA3/SULF2-07793-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-NCOA3/SULF2-07793-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-NCOA3/SULF2-07793-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-NCOA3/SULF2-07793-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-NCOA3/SULF2-07793-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-NCOA3/SULF2-07793-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-NCOA3/SULF2-07793-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-NCOA3/SULF2-07793-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-NCOA3/SULF2-07793-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-NCOA3/SULF2-07793-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-NCOA3/SULF2-07793-AQAQ |
467nm;467nm |
418nm;418nm |
|
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