NCOA2-NCALD Gene Fusion FISH Probe
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Catalog: |
GFFP-NCOA2/NCALD-07804 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The NCOA2-NCALD Gene Fusion FISH Probecan detect the fusion of NCOA2 and NCALD genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
NCOA2-NCALD Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Nuclear Receptor Coactivator 2 |
Gene Summary 1 |
The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
Chromosome 1 |
Chromosome 8 |
Locus 1 |
8q13.3 |
Coordinates 1 |
This gene maps to 71024266-71316020 in GRCh37 coordinates. |
Gene Name 2 |
Neurocalcin Delta |
Gene Summary 2 |
This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome8 |
Locus 2 |
8q22.3 |
Coordinates 2 |
This gene maps to 102698769-103137135 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-NCOA2/NCALD-07804-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-NCOA2/NCALD-07804-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-NCOA2/NCALD-07804-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-NCOA2/NCALD-07804-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-NCOA2/NCALD-07804-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-NCOA2/NCALD-07804-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-NCOA2/NCALD-07804-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-NCOA2/NCALD-07804-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-NCOA2/NCALD-07804-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-NCOA2/NCALD-07804-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-NCOA2/NCALD-07804-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-NCOA2/NCALD-07804-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-NCOA2/NCALD-07804-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-NCOA2/NCALD-07804-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-NCOA2/NCALD-07804-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-NCOA2/NCALD-07804-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-NCOA2/NCALD-07804-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-NCOA2/NCALD-07804-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-NCOA2/NCALD-07804-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-NCOA2/NCALD-07804-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-NCOA2/NCALD-07804-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-NCOA2/NCALD-07804-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-NCOA2/NCALD-07804-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-NCOA2/NCALD-07804-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-NCOA2/NCALD-07804-AQAQ |
467nm;467nm |
418nm;418nm |
|
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