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NCALD-NSMCE2 Gene Fusion FISH Probe

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Catalog: GFFP-NCALD/NSMCE2-07531
Classification: Gene Fusion FISH Probes
Description: The NCALD-NSMCE2 Gene Fusion FISH Probecan detect the fusion of NCALD and NSMCE2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NCALD-NSMCE2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Neurocalcin Delta
Gene Summary 1 This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 8
Locus 1 8q22.3
Coordinates 1 This gene maps to 102698769-103137135 in GRCh37 coordinates.
Gene Name 2 NSE2/MMS21 Homolog, SMC5-SMC6 Complex SUMO Ligase
Gene Summary 2 This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance. [provided by RefSeq, Mar 2017]
Chromosome 2 Chromosome8
Locus 2 8q24.13
Coordinates 2 This gene maps to 126104082-126379367 in GRCh37 coordinates.
Associated Diseases Lung Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NCALD/NSMCE2-07531-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NCALD/NSMCE2-07531-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NCALD/NSMCE2-07531-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NCALD/NSMCE2-07531-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NCALD/NSMCE2-07531-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NCALD/NSMCE2-07531-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NCALD/NSMCE2-07531-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NCALD/NSMCE2-07531-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NCALD/NSMCE2-07531-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NCALD/NSMCE2-07531-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NCALD/NSMCE2-07531-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NCALD/NSMCE2-07531-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NCALD/NSMCE2-07531-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NCALD/NSMCE2-07531-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NCALD/NSMCE2-07531-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NCALD/NSMCE2-07531-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NCALD/NSMCE2-07531-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NCALD/NSMCE2-07531-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NCALD/NSMCE2-07531-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NCALD/NSMCE2-07531-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NCALD/NSMCE2-07531-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NCALD/NSMCE2-07531-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NCALD/NSMCE2-07531-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NCALD/NSMCE2-07531-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NCALD/NSMCE2-07531-AQAQ 467nm;467nm 418nm;418nm

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