NBN-RIPK2 Gene Fusion FISH Probe
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Catalog: |
GFFP-NBN/RIPK2-07534 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The NBN-RIPK2 Gene Fusion FISH Probecan detect the fusion of NBN and RIPK2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
NBN-RIPK2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Nibrin |
Gene Summary 1 |
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 8 |
Locus 1 |
8q21.3 |
Coordinates 1 |
This gene maps to 90945563-90996899 in GRCh37 coordinates. |
Gene Name 2 |
Receptor Interacting Serine/threonine Kinase 2 |
Gene Summary 2 |
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome8 |
Locus 2 |
8q21.3 |
Coordinates 2 |
This gene maps to 90769974-90803292 in GRCh37 coordinates. |
Associated Diseases |
Bladder Urothelial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-NBN/RIPK2-07534-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-NBN/RIPK2-07534-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-NBN/RIPK2-07534-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-NBN/RIPK2-07534-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-NBN/RIPK2-07534-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-NBN/RIPK2-07534-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-NBN/RIPK2-07534-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-NBN/RIPK2-07534-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-NBN/RIPK2-07534-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-NBN/RIPK2-07534-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-NBN/RIPK2-07534-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-NBN/RIPK2-07534-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-NBN/RIPK2-07534-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-NBN/RIPK2-07534-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-NBN/RIPK2-07534-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-NBN/RIPK2-07534-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-NBN/RIPK2-07534-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-NBN/RIPK2-07534-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-NBN/RIPK2-07534-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-NBN/RIPK2-07534-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-NBN/RIPK2-07534-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-NBN/RIPK2-07534-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-NBN/RIPK2-07534-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-NBN/RIPK2-07534-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-NBN/RIPK2-07534-AQAQ |
467nm;467nm |
418nm;418nm |
|
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