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NAPSA-SEC63 Gene Fusion FISH Probe

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Catalog: GFFP-NAPSA/SEC63-07553
Classification: Gene Fusion FISH Probes
Description: The NAPSA-SEC63 Gene Fusion FISH Probecan detect the fusion of NAPSA and SEC63 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NAPSA-SEC63 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Napsin A Aspartic Peptidase
Gene Summary 1 This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]
Chromosome 1 Chromosome 19
Locus 1 19q13.33
Coordinates 1 This gene maps to 50861733-50868931 in GRCh37 coordinates.
Gene Name 2 SEC63 Homolog, Protein Translocation Regulator
Gene Summary 2 The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome6
Locus 2 6q21
Coordinates 2 This gene maps to 108188959-108279482 in GRCh37 coordinates.
Associated Diseases Lung Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NAPSA/SEC63-07553-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NAPSA/SEC63-07553-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NAPSA/SEC63-07553-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NAPSA/SEC63-07553-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NAPSA/SEC63-07553-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NAPSA/SEC63-07553-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NAPSA/SEC63-07553-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NAPSA/SEC63-07553-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NAPSA/SEC63-07553-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NAPSA/SEC63-07553-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NAPSA/SEC63-07553-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NAPSA/SEC63-07553-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NAPSA/SEC63-07553-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NAPSA/SEC63-07553-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NAPSA/SEC63-07553-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NAPSA/SEC63-07553-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NAPSA/SEC63-07553-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NAPSA/SEC63-07553-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NAPSA/SEC63-07553-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NAPSA/SEC63-07553-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NAPSA/SEC63-07553-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NAPSA/SEC63-07553-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NAPSA/SEC63-07553-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NAPSA/SEC63-07553-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NAPSA/SEC63-07553-AQAQ 467nm;467nm 418nm;418nm

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