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NAB2-STAT6 Gene Fusion FISH Probe

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Catalog: GFFP-NAB2/STAT6-07575
Classification: Gene Fusion FISH Probes
Description: The NAB2-STAT6 Gene Fusion FISH Probecan detect the fusion of NAB2 and STAT6 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: NAB2-STAT6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 NGFI-A Binding Protein 2
Gene Summary 1 This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 12
Locus 1 12q13.3
Coordinates 1 This gene maps to 57482676-57489259 in GRCh37 coordinates.
Gene Name 2 Signal Transducer And Activator Of Transcription 6
Gene Summary 2 The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Chromosome 2 Chromosome12
Locus 2 12q13.3
Coordinates 2 This gene maps to 57489186-57505196 in GRCh37 coordinates.
Associated Diseases Mesothelioma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-NAB2/STAT6-07575-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-NAB2/STAT6-07575-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-NAB2/STAT6-07575-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-NAB2/STAT6-07575-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-NAB2/STAT6-07575-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-NAB2/STAT6-07575-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-NAB2/STAT6-07575-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-NAB2/STAT6-07575-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-NAB2/STAT6-07575-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-NAB2/STAT6-07575-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-NAB2/STAT6-07575-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-NAB2/STAT6-07575-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-NAB2/STAT6-07575-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-NAB2/STAT6-07575-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-NAB2/STAT6-07575-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-NAB2/STAT6-07575-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-NAB2/STAT6-07575-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-NAB2/STAT6-07575-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-NAB2/STAT6-07575-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-NAB2/STAT6-07575-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-NAB2/STAT6-07575-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-NAB2/STAT6-07575-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-NAB2/STAT6-07575-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-NAB2/STAT6-07575-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-NAB2/STAT6-07575-AQAQ 467nm;467nm 418nm;418nm

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