MYO7A-GAB2 Gene Fusion FISH Probe
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Catalog: |
GFFP-MYO7A/GAB2-07620 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MYO7A-GAB2 Gene Fusion FISH Probecan detect the fusion of MYO7A and GAB2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MYO7A-GAB2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Myosin VIIA |
Gene Summary 1 |
This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11q13.5 |
Coordinates 1 |
This gene maps to 76839309-76926286 in GRCh37 coordinates. |
Gene Name 2 |
GRB2 Associated Binding Protein 2 |
Gene Summary 2 |
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q14.1 |
Coordinates 2 |
This gene maps to 77926335-78128868 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MYO7A/GAB2-07620-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MYO7A/GAB2-07620-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MYO7A/GAB2-07620-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MYO7A/GAB2-07620-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MYO7A/GAB2-07620-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MYO7A/GAB2-07620-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MYO7A/GAB2-07620-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MYO7A/GAB2-07620-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MYO7A/GAB2-07620-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MYO7A/GAB2-07620-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MYO7A/GAB2-07620-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MYO7A/GAB2-07620-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MYO7A/GAB2-07620-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MYO7A/GAB2-07620-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MYO7A/GAB2-07620-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MYO7A/GAB2-07620-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MYO7A/GAB2-07620-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MYO7A/GAB2-07620-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MYO7A/GAB2-07620-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MYO7A/GAB2-07620-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MYO7A/GAB2-07620-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MYO7A/GAB2-07620-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MYO7A/GAB2-07620-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MYO7A/GAB2-07620-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MYO7A/GAB2-07620-AQAQ |
467nm;467nm |
418nm;418nm |
|
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