MYO1C-SMG6 Gene Fusion FISH Probe
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Catalog: |
GFFP-MYO1C/SMG6-07637 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MYO1C-SMG6 Gene Fusion FISH Probecan detect the fusion of MYO1C and SMG6 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MYO1C-SMG6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Myosin IC |
Gene Summary 1 |
This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17p13.3 |
Coordinates 1 |
This gene maps to 1367479-1396001 in GRCh37 coordinates. |
Gene Name 2 |
SMG6, Nonsense Mediated MRNA Decay Factor |
Gene Summary 2 |
This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described. [provided by RefSeq, Feb 2014] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17p13.3 |
Coordinates 2 |
This gene maps to 1963132-2207069 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MYO1C/SMG6-07637-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MYO1C/SMG6-07637-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MYO1C/SMG6-07637-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MYO1C/SMG6-07637-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MYO1C/SMG6-07637-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MYO1C/SMG6-07637-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MYO1C/SMG6-07637-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MYO1C/SMG6-07637-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MYO1C/SMG6-07637-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MYO1C/SMG6-07637-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MYO1C/SMG6-07637-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MYO1C/SMG6-07637-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MYO1C/SMG6-07637-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MYO1C/SMG6-07637-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MYO1C/SMG6-07637-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MYO1C/SMG6-07637-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MYO1C/SMG6-07637-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MYO1C/SMG6-07637-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MYO1C/SMG6-07637-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MYO1C/SMG6-07637-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MYO1C/SMG6-07637-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MYO1C/SMG6-07637-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MYO1C/SMG6-07637-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MYO1C/SMG6-07637-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MYO1C/SMG6-07637-AQAQ |
467nm;467nm |
418nm;418nm |
|
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