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MTMR2-MAML2 Gene Fusion FISH Probe

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Catalog: GFFP-MTMR2/MAML2-15331
Classification: Gene Fusion FISH Probes
Description: The MTMR2-MAML2 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MTMR2-MAML2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Myotubularin Related Protein 2
Gene Summary 1 This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Chromosome 1 Chromosome 11
Locus 1 11q21
Coordinates 1 This gene maps to 95566043-95657371in GRCh37 coordinates.
Gene Name 2 Mastermind Like Transcriptional Coactivator 2
Gene Summary 2 The protein encoded by this gene is a member of the Mastermind-like family of proteins. All family members are proline and glutamine-rich, and contain a conserved basic domain that binds the ankyrin repeat domain of the intracellular domain of the Notch receptors (ICN1-4) in their N-terminus, and a transcriptional activation domain in their C-terminus. This protein binds to an extended groove that is formed by the interaction of CBF1, Suppressor of Hairless, LAG-1 (CSL) with ICN, and positively regulates Notch signaling. High levels of expression of this gene have been observed in several B cell-derived lymphomas. Translocations resulting in fusion proteins with both CRTC1 and CRTC3 have been implicated in the development of mucoepidermoid carcinomas, while a translocation event with CXCR4 has been linked with chronic lymphocytic leukemia (CLL). Copy number variation in the polyglutamine tract has been observed. [provided by RefSeq, Jan 2015]
Chromosome 2 Chromosome11
Locus 2 11q21
Coordinates 2 This gene maps to 95711439-96076344 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma; Brain Lower Grade Glioma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MTMR2/MAML2-15331-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MTMR2/MAML2-15331-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MTMR2/MAML2-15331-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MTMR2/MAML2-15331-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MTMR2/MAML2-15331-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MTMR2/MAML2-15331-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MTMR2/MAML2-15331-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MTMR2/MAML2-15331-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MTMR2/MAML2-15331-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MTMR2/MAML2-15331-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MTMR2/MAML2-15331-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MTMR2/MAML2-15331-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MTMR2/MAML2-15331-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MTMR2/MAML2-15331-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MTMR2/MAML2-15331-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MTMR2/MAML2-15331-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MTMR2/MAML2-15331-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MTMR2/MAML2-15331-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MTMR2/MAML2-15331-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MTMR2/MAML2-15331-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MTMR2/MAML2-15331-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MTMR2/MAML2-15331-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MTMR2/MAML2-15331-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MTMR2/MAML2-15331-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MTMR2/MAML2-15331-AQAQ 467nm;467nm 418nm;418nm

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