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MSH5-BSCL2 Gene Fusion FISH Probe

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Catalog: GFFP-MSH5/BSCL2-07476
Classification: Gene Fusion FISH Probes
Description: The MSH5-BSCL2 Gene Fusion FISH Probecan detect the fusion of MSH5 and BSCL2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MSH5-BSCL2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 MutS Homolog 5
Gene Summary 1 This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. [provided by RefSeq, Feb 2011]
Chromosome 1 Chromosome 6_mcf_hap5
Locus 1 6p21.33
Coordinates 1 This gene maps to 3087408-3110152 in GRCh37 coordinates.
Gene Name 2 BSCL2, Seipin Lipid Droplet Biogenesis Associated
Gene Summary 2 This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).[provided by RefSeq, Mar 2011]
Chromosome 2 Chromosome11
Locus 2 11q12.3
Coordinates 2 This gene maps to 62457733-62477091 in GRCh37 coordinates.
Associated Diseases Adrenocortical Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MSH5/BSCL2-07476-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MSH5/BSCL2-07476-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MSH5/BSCL2-07476-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MSH5/BSCL2-07476-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MSH5/BSCL2-07476-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MSH5/BSCL2-07476-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MSH5/BSCL2-07476-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MSH5/BSCL2-07476-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MSH5/BSCL2-07476-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MSH5/BSCL2-07476-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MSH5/BSCL2-07476-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MSH5/BSCL2-07476-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MSH5/BSCL2-07476-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MSH5/BSCL2-07476-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MSH5/BSCL2-07476-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MSH5/BSCL2-07476-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MSH5/BSCL2-07476-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MSH5/BSCL2-07476-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MSH5/BSCL2-07476-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MSH5/BSCL2-07476-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MSH5/BSCL2-07476-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MSH5/BSCL2-07476-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MSH5/BSCL2-07476-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MSH5/BSCL2-07476-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MSH5/BSCL2-07476-AQAQ 467nm;467nm 418nm;418nm

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