MSH2-SPTLC1 Gene Fusion FISH Probe
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Catalog: |
GFFP-MSH2/SPTLC1-07485 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MSH2-SPTLC1 Gene Fusion FISH Probecan detect the fusion of MSH2 and SPTLC1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MSH2-SPTLC1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
MutS Homolog 2 |
Gene Summary 1 |
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
Chromosome 1 |
Chromosome 2 |
Locus 1 |
2p21-p16.3 |
Coordinates 1 |
This gene maps to 47630262-47710360 in GRCh37 coordinates. |
Gene Name 2 |
Serine Palmitoyltransferase Long Chain Base Subunit 1 |
Gene Summary 2 |
This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013] |
Chromosome 2 |
Chromosome9 |
Locus 2 |
9q22.31 |
Coordinates 2 |
This gene maps to 94793426-94877690 in GRCh37 coordinates. |
Associated Diseases |
Uterine Carcinosarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MSH2/SPTLC1-07485-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MSH2/SPTLC1-07485-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MSH2/SPTLC1-07485-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MSH2/SPTLC1-07485-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MSH2/SPTLC1-07485-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MSH2/SPTLC1-07485-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MSH2/SPTLC1-07485-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MSH2/SPTLC1-07485-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MSH2/SPTLC1-07485-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MSH2/SPTLC1-07485-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MSH2/SPTLC1-07485-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MSH2/SPTLC1-07485-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MSH2/SPTLC1-07485-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MSH2/SPTLC1-07485-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MSH2/SPTLC1-07485-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MSH2/SPTLC1-07485-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MSH2/SPTLC1-07485-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MSH2/SPTLC1-07485-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MSH2/SPTLC1-07485-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MSH2/SPTLC1-07485-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MSH2/SPTLC1-07485-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MSH2/SPTLC1-07485-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MSH2/SPTLC1-07485-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MSH2/SPTLC1-07485-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MSH2/SPTLC1-07485-AQAQ |
467nm;467nm |
418nm;418nm |
|
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