MRPL21-SSH3 Gene Fusion FISH Probe
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Catalog: |
GFFP-MRPL21/SSH3-07158 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MRPL21-SSH3 Gene Fusion FISH Probecan detect the fusion of MRPL21 and SSH3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MRPL21-SSH3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Slingshot Protein Phosphatase 3 |
Gene Summary 1 |
The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM, Mar 2008] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11q13.2 |
Coordinates 1 |
This gene maps to 67070918-67080078 in GRCh37 coordinates. |
Gene Name 2 |
Mitochondrial Ribosomal Protein L21 |
Gene Summary 2 |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q13.3 |
Coordinates 2 |
This gene maps to 68658745-68671303 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MRPL21/SSH3-07158-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MRPL21/SSH3-07158-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MRPL21/SSH3-07158-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MRPL21/SSH3-07158-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MRPL21/SSH3-07158-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MRPL21/SSH3-07158-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MRPL21/SSH3-07158-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MRPL21/SSH3-07158-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MRPL21/SSH3-07158-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MRPL21/SSH3-07158-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MRPL21/SSH3-07158-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MRPL21/SSH3-07158-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MRPL21/SSH3-07158-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MRPL21/SSH3-07158-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MRPL21/SSH3-07158-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MRPL21/SSH3-07158-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MRPL21/SSH3-07158-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MRPL21/SSH3-07158-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MRPL21/SSH3-07158-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MRPL21/SSH3-07158-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MRPL21/SSH3-07158-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MRPL21/SSH3-07158-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MRPL21/SSH3-07158-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MRPL21/SSH3-07158-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MRPL21/SSH3-07158-AQAQ |
467nm;467nm |
418nm;418nm |
|
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