MMP14-RBM23 Gene Fusion FISH Probe
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Catalog: |
GFFP-MMP14/RBM23-07226 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MMP14-RBM23 Gene Fusion FISH Probecan detect the fusion of MMP14 and RBM23 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MMP14-RBM23 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Matrix Metallopeptidase 14 |
Gene Summary 1 |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 14 |
Locus 1 |
14q11.2 |
Coordinates 1 |
This gene maps to 23305792-23316803 in GRCh37 coordinates. |
Gene Name 2 |
RNA Binding Motif Protein 23 |
Gene Summary 2 |
This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptional reporters in a hormone-dependent manner. It is also implicated in the steroid receptor-dependent regulation of alternative splicing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome14 |
Locus 2 |
14q11.2 |
Coordinates 2 |
This gene maps to 23369853-23388396 in GRCh37 coordinates. |
Associated Diseases |
Kidney Chromophobe |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MMP14/RBM23-07226-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MMP14/RBM23-07226-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MMP14/RBM23-07226-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MMP14/RBM23-07226-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MMP14/RBM23-07226-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MMP14/RBM23-07226-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MMP14/RBM23-07226-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MMP14/RBM23-07226-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MMP14/RBM23-07226-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MMP14/RBM23-07226-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MMP14/RBM23-07226-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MMP14/RBM23-07226-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MMP14/RBM23-07226-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MMP14/RBM23-07226-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MMP14/RBM23-07226-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MMP14/RBM23-07226-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MMP14/RBM23-07226-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MMP14/RBM23-07226-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MMP14/RBM23-07226-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MMP14/RBM23-07226-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MMP14/RBM23-07226-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MMP14/RBM23-07226-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MMP14/RBM23-07226-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MMP14/RBM23-07226-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MMP14/RBM23-07226-AQAQ |
467nm;467nm |
418nm;418nm |
|
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