MMP14-CCT5 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-MMP14/CCT5-07228 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MMP14-CCT5 Gene Fusion FISH Probecan detect the fusion of MMP14 and CCT5 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MMP14-CCT5 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Matrix Metallopeptidase 14 |
Gene Summary 1 |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 14 |
Locus 1 |
14q11.2 |
Coordinates 1 |
This gene maps to 23305792-23316803 in GRCh37 coordinates. |
Gene Name 2 |
Chaperonin Containing TCP1 Subunit 5 |
Gene Summary 2 |
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015] |
Chromosome 2 |
Chromosome5 |
Locus 2 |
5p15.2 |
Coordinates 2 |
This gene maps to 10250281-10266501 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MMP14/CCT5-07228-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MMP14/CCT5-07228-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MMP14/CCT5-07228-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MMP14/CCT5-07228-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MMP14/CCT5-07228-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MMP14/CCT5-07228-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MMP14/CCT5-07228-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MMP14/CCT5-07228-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MMP14/CCT5-07228-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MMP14/CCT5-07228-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MMP14/CCT5-07228-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MMP14/CCT5-07228-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MMP14/CCT5-07228-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MMP14/CCT5-07228-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MMP14/CCT5-07228-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MMP14/CCT5-07228-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MMP14/CCT5-07228-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MMP14/CCT5-07228-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MMP14/CCT5-07228-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MMP14/CCT5-07228-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MMP14/CCT5-07228-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MMP14/CCT5-07228-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MMP14/CCT5-07228-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MMP14/CCT5-07228-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MMP14/CCT5-07228-AQAQ |
467nm;467nm |
418nm;418nm |
|
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