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MKLN1-GRM8 Gene Fusion FISH Probe

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Catalog: GFFP-MKLN1/GRM8-07298
Classification: Gene Fusion FISH Probes
Description: The MKLN1-GRM8 Gene Fusion FISH Probecan detect the fusion of MKLN1 and GRM8 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MKLN1-GRM8 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Glutamate Metabotropic Receptor 8
Gene Summary 1 L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 7
Locus 1 7q31.33
Coordinates 1 This gene maps to 126078651-126892428 in GRCh37 coordinates.
Gene Name 2 Muskelin 1
Gene Summary 2 Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008]
Chromosome 2 Chromosome7
Locus 2 7q32.3
Coordinates 2 This gene maps to 130794854-131181398 in GRCh37 coordinates.
Associated Diseases Skin Cutaneous Melanoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MKLN1/GRM8-07298-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MKLN1/GRM8-07298-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MKLN1/GRM8-07298-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MKLN1/GRM8-07298-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MKLN1/GRM8-07298-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MKLN1/GRM8-07298-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MKLN1/GRM8-07298-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MKLN1/GRM8-07298-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MKLN1/GRM8-07298-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MKLN1/GRM8-07298-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MKLN1/GRM8-07298-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MKLN1/GRM8-07298-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MKLN1/GRM8-07298-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MKLN1/GRM8-07298-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MKLN1/GRM8-07298-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MKLN1/GRM8-07298-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MKLN1/GRM8-07298-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MKLN1/GRM8-07298-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MKLN1/GRM8-07298-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MKLN1/GRM8-07298-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MKLN1/GRM8-07298-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MKLN1/GRM8-07298-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MKLN1/GRM8-07298-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MKLN1/GRM8-07298-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MKLN1/GRM8-07298-AQAQ 467nm;467nm 418nm;418nm

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