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METAP2-VEZT Gene Fusion FISH Probe

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Catalog: GFFP-METAP2/VEZT-15295
Classification: Gene Fusion FISH Probes
Description: The METAP2-VEZT Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: METAP2-VEZT Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Methionyl Aminopeptidase 2
Gene Summary 1 The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Chromosome 1 Chromosome 12
Locus 1 12q22
Coordinates 1 This gene maps to 95867821-95909613in GRCh37 coordinates.
Gene Name 2 Vezatin, Adherens Junctions Transmembrane Protein
Gene Summary 2 This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
Chromosome 2 Chromosome12
Locus 2 12q22
Coordinates 2 This gene maps to 95611521-95696566 in GRCh37 coordinates.
Associated Diseases Liver Hepatocellular Carcinoma; Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-METAP2/VEZT-15295-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-METAP2/VEZT-15295-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-METAP2/VEZT-15295-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-METAP2/VEZT-15295-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-METAP2/VEZT-15295-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-METAP2/VEZT-15295-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-METAP2/VEZT-15295-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-METAP2/VEZT-15295-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-METAP2/VEZT-15295-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-METAP2/VEZT-15295-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-METAP2/VEZT-15295-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-METAP2/VEZT-15295-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-METAP2/VEZT-15295-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-METAP2/VEZT-15295-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-METAP2/VEZT-15295-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-METAP2/VEZT-15295-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-METAP2/VEZT-15295-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-METAP2/VEZT-15295-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-METAP2/VEZT-15295-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-METAP2/VEZT-15295-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-METAP2/VEZT-15295-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-METAP2/VEZT-15295-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-METAP2/VEZT-15295-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-METAP2/VEZT-15295-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-METAP2/VEZT-15295-AQAQ 467nm;467nm 418nm;418nm

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